Long non-coding RNAs in cardiovascular diseases: potential function as biomarkers and therapeutic targets of exercise training

CCM Correia, LF Rodrigues, BR de Avila Pelozin… - Non-coding RNA, 2021 - mdpi.com
Despite advances in treatments and therapies, cardiovascular diseases (CVDs) remain one
of the leading causes of death worldwide. The discovery that most of the human genome …

Noncoding RNAs in cardiac hypertrophy and heart failure

P Lu, F Ding, YK Xiang, L Hao, M Zhao - Cells, 2022 - mdpi.com
Heart failure is a major global health concern. Noncoding RNAs (ncRNAs) are involved in
physiological processes and in the pathogenesis of various diseases, including heart failure …

Predictive biomarkers for the early detection and management of heart failure

V Mariappan, R Srinivasan, R Pratheesh… - Heart Failure …, 2024 - Springer
Cardiovascular disease (CVD) is a serious public health concern whose incidence has been
on a rise and is projected by the World Health Organization to be the leading global cause of …

Probing lncRNA–protein interactions: data repositories, models, and algorithms

L Peng, F Liu, J Yang, X Liu, Y Meng, X Deng… - Frontiers in …, 2020 - frontiersin.org
Identifying lncRNA–protein interactions (LPIs) is vital to understanding various key biological
processes. Wet experiments found a few LPIs, but experimental methods are costly and time …

lncRNAs–mRNAs Co–Expression Network Underlying Childhood B–Cell Acute Lymphoblastic Leukaemia: A Pilot Study

O Affinito, K Pane, G Smaldone, FM Orlandella… - Cancers, 2020 - mdpi.com
Simple Summary Acute lymphoblastic leukemia (ALL) is one of the most common childhood
cancers. The ALL onset involves abnormal proliferation and arrest of differentiation of B or T …

Preliminary RNA-seq analysis of long non-coding RNAs expressed in human term placenta

M Majewska, A Lipka, L Paukszto… - International journal of …, 2018 - mdpi.com
Development of particular structures and proper functioning of the placenta are under the
influence of sophisticated pathways, controlled by the expression of substantial genes that …

Effect of the consumption of hesperidin in orange juice on the transcriptomic profile of subjects with elevated blood pressure and stage 1 hypertension: A randomized …

L Pla-Pagà, RM Valls, A Pedret, L Calderón-Pérez… - Clinical Nutrition, 2021 - Elsevier
Scope Hesperidin exerts cardiovascular beneficial effects, but its mechanisms of action
remain undefined. In a previous study we demonstrated that a single dose and a 12-week …

A novel long noncoding RNA—lncRNA‐AABR07066529. 3 alleviates inflammation, apoptosis, and pyroptosis by inhibiting MyD88 in lipopolysaccharide‐induced …

R Wen, TN Zhang, T Zhang, YJ Tong… - The FASEB …, 2023 - Wiley Online Library
Sepsis‐induced myocardial depression (SIMD) is common in pediatric intensive care units
and seriously threatens children's health. Recently, long noncoding RNAs (lncRNAs) have …

Data-driven microbiota biomarker discovery for personalized drug therapy of cardiovascular disease

L Shen, K Shen, J Bai, J Wang, RK Singla… - Pharmacological …, 2020 - Elsevier
Cardiovascular disease (CVD) is the most wide-spread disorder all over the world. The
personalized and precision diagnosis, treatment and prevention of CVD is still a challenge …

Dysregulated lncRNA-miRNA-mRNA network reveals patient survival-associated modules and RNA binding proteins in invasive breast carcinoma

Y Dong, Y Xiao, Q Shi, C Jiang - Frontiers in genetics, 2020 - frontiersin.org
Breast cancer is the most common cancer in women, but few biomarkers are effective in
clinic. Previous studies have shown the important roles of non-coding RNAs in diagnosis …