Neuropathic pain
L Colloca, T Ludman, D Bouhassira, R Baron… - Nature reviews Disease …, 2017 - nature.com
Neuropathic pain is caused by a lesion or disease of the somatosensory system, including
peripheral fibres (Aβ, Aδ and C fibres) and central neurons, and affects 7–10% of the …
peripheral fibres (Aβ, Aδ and C fibres) and central neurons, and affects 7–10% of the …
Antidepressants and gabapentinoids in neuropathic pain: mechanistic insights
Neuropathic pain arises as a consequence of a lesion or disease affecting the
somatosensory system. It is generally chronic and challenging to treat. The recommended …
somatosensory system. It is generally chronic and challenging to treat. The recommended …
Tests and models of nociception and pain in rodents
M Barrot - Neuroscience, 2012 - Elsevier
Nociception and pain is a large field of both neuroscience and medical research. Over time,
various tests and models were developed in rodents to provide tools for fundamental and …
various tests and models were developed in rodents to provide tools for fundamental and …
Animal models of neuropathic pain
Animal models are pivotal for understanding the mechanism of neuropathic pain and
development of effective therapy for its optimal management. A battery of neuropathic pain …
development of effective therapy for its optimal management. A battery of neuropathic pain …
Pharmacological treatments of neuropathic pain: The latest recommendations
N Attal - Revue neurologique, 2019 - Elsevier
We provide an up-to-date review of the pharmacological treatment of neuropathic pain with
emphasis on the latest evidence-based recommendations for its pharmacological treatment …
emphasis on the latest evidence-based recommendations for its pharmacological treatment …
Pharmacotherapy of neuropathic pain: which drugs, which treatment algorithms?
N Attal, D Bouhassira - Pain, 2015 - journals.lww.com
Neuropathic pain (NP) is a significant medical and socioeconomic burden. Epidemiological
surveys have indicated that many patients with NP do not receive appropriate treatment for …
surveys have indicated that many patients with NP do not receive appropriate treatment for …
A time-dependent history of mood disorders in a murine model of neuropathic pain
I Yalcin, Y Bohren, E Waltisperger, D Sage-Ciocca… - Biological …, 2011 - Elsevier
BACKGROUND: Chronic pain is clinically associated with the development of affective
disorders. However, studies in animal models of neuropathic pain are contradictory and the …
disorders. However, studies in animal models of neuropathic pain are contradictory and the …
Neuropathic pain and spinal cord injury: phenotypes and pharmacological management
E Widerström-Noga - Drugs, 2017 - Springer
Chronic neuropathic pain is a complicated condition after a spinal cord injury (SCI) that often
has a lifelong and significant negative impact on life after the injury; therefore, improved pain …
has a lifelong and significant negative impact on life after the injury; therefore, improved pain …
A dual noradrenergic mechanism for the relief of neuropathic allodynia by the antidepressant drugs duloxetine and amitriptyline
In addition to treating depression, antidepressant drugs are also a first-line treatment for
neuropathic pain, which is pain secondary to lesion or pathology of the nervous system …
neuropathic pain, which is pain secondary to lesion or pathology of the nervous system …
Curcumin exerts antinociceptive effects in a mouse model of neuropathic pain: descending monoamine system and opioid receptors are differentially involved
Curcumin, a phenolic compound present in Curcuma longa, has been reported to exert
antinociceptive effects in some animal models, but the mechanisms remain to be elucidated …
antinociceptive effects in some animal models, but the mechanisms remain to be elucidated …