Being a leading lethal malignancy worldwide, the pathophysiology of hepatocellular
carcinoma (HCC) has gained a lot of interest. Yet, underlying mechanistic basis of the liver …

Hepatocellular carcinoma (HCC) is a highly fatal malignancy with limited therapeutic options
and high recurrence rates. Recently, immunotherapeutic agents such as immune checkpoint …

A non-negligible part of our DNA has been proven to be transcribed into non-protein coding
RNA and its intricate involvement in several physiological processes has been highly …

Recently, myriad studies have defined the versatile abilities of gasotransmitters and their
synthesizing enzymes to play a “Maestro” role in orchestrating several oncological and non …

Circular RNAs (circRNAs) are cardinal players in numerous physiological and pathological
processes. CircRNAs play dual roles as tumor suppressors and oncogenes in different …

The discovery of non-coding RNAs (ncRNAs) has unveiled a wide range of transcripts that
do not encode proteins but play key roles in several cellular and molecular processes. Long …

The concept of 'Hallmarks of Cancer'is an approach of reducing the enormous complexity of
cancer to a set of guiding principles. As the underlying mechanism of cancer are portrayed …

The host immune system status remains an unresolved mystery among several
malignancies. An immune-compromised state or smart immune-surveillance tactics …

Abstract Background Hydrogen sulfide (H2S) is a significant endogenous mediator that has
been implicated in the progression of various forms of cancer including breast cancer (BC) …

Tumor microenvironment is an intricate web of stromal and immune cells creating an
immune suppressive cordon around the tumor. In hepatocellular carcinoma (HCC), Tumor …