Advances and opportunities in the exciting world of azobenzenes

FA Jerca, VV Jerca, R Hoogenboom - Nature Reviews Chemistry, 2022 - nature.com
Azobenzenes are archetypal molecules that have a central role in fundamental and applied
research. Over the course of almost two centuries, the area of azobenzenes has witnessed …

Stimulus-cleavable chemistry in the field of controlled drug delivery

Y Xue, H Bai, B Peng, B Fang, J Baell, L Li… - Chemical Society …, 2021 - pubs.rsc.org
Stimulus-cleavable nanoscale drug delivery systems are receiving significant attention
owing to their capability of achieving exquisite control over drug release via the exposure to …

Triggered azobenzene-based prodrugs and drug delivery systems

J Zhu, T Guo, Z Wang, Y Zhao - Journal of Controlled Release, 2022 - Elsevier
Azobenzene-based molecules show unique trans-cis isomerization upon ultraviolet light
irradiation, which induce the change of polarity, crystallinity, stability, and binding affinity with …

Metal-coordinated azoaromatics: Strategies for sequential azo-reduction, isomerization and application potential

S Panda, S Dhara, A Singh, S Dey, GK Lahiri - Coordination Chemistry …, 2023 - Elsevier
Reversible electron reservoir feature of redox non-innocent ligand is an important event from
the broader perspectives of metal–ligand cooperativity in catalysis as well as in introducing …

Perspectives about self-immolative drug delivery systems

RV Gonzaga, LA do Nascimento, SS Santos… - Journal of …, 2020 - Elsevier
Self-immolative drug delivery system is one of the delivery systems, which have drawn
attention, in recent research, highlighting the improvement they generate in drug selectivity …

Stimuli‐responsive prodrug chemistries for drug delivery

V Taresco, C Alexander, N Singh… - Advanced …, 2018 - Wiley Online Library
Research into advanced therapeutic materials is of growing importance worldwide,
particularly in the disease areas of infection, neurodegeneration, and oncology. Advances …

Biologically activatable azobenzene polymers targeted at drug delivery and imaging applications

T Eom, W Yoo, S Kim, A Khan - Biomaterials, 2018 - Elsevier
Molecular design concepts are described for the preparation of azobenzene polymers
capable of showing a tunable response to the rat liver microsome-induced side-chain self …

Untapped potential for debonding on demand: the wonderful world of azo-compounds

H Mutlu, CM Geiselhart, C Barner-Kowollik - Materials Horizons, 2018 - pubs.rsc.org
We highlight and explore recent advances in the design of debonding on demand soft
matter materials based on the azo-motif. While azo-motifs are most frequently exploited for …

Rethinking nanoparticulate polymer–drug conjugates for cancer theranostics

Y Wang, H Xia, B Chen, Y Wang - … Reviews: Nanomedicine and …, 2023 - Wiley Online Library
Polymer–drug conjugates (PDCs) fabricated as nanoparticles have hogged the limelight in
cancer theranostics in the past decade. Many researchers have devoted to developing novel …

Carboxymethyl dextran-based hypoxia-responsive nanoparticles for doxorubicin delivery

S Son, NV Rao, H Ko, S Shin, J Jeon, HS Han… - International journal of …, 2018 - Elsevier
In an attempt to develop the hypoxia-responsive nanoparticles for cancer therapy, a polymer
conjugate, consisting of carboxymethyl dextran (CMD) and black hole quencher 3 (BHQ3) …