Precision medicine with multi-omics strategies, deep phenotyping, and predictive analysis

Z Ahmed - Progress in molecular biology and translational …, 2022 - Elsevier
Precision medicine is driven by the paradigm shift of empowering clinicians to predict the
most appropriate course of action for patients with complex diseases and to improve routine …

Applications of artificial intelligence multiomics in precision oncology

R Srivastava - Journal of cancer research and clinical oncology, 2023 - Springer
Cancer is the second leading worldwide disease that depends on oncogenic mutations and
non-mutated genes for survival. Recent advancements in next-generation sequencing …

[HTML][HTML] Practicing precision medicine with intelligently integrative clinical and multi-omics data analysis

Z Ahmed - Human genomics, 2020 - Springer
Precision medicine aims to empower clinicians to predict the most appropriate course of
action for patients with complex diseases like cancer, diabetes, cardiomyopathy, and COVID …

Human gene and disease associations for clinical‐genomics and precision medicine research

Z Ahmed, S Zeeshan, D Mendhe… - Clinical and translational …, 2020 - Wiley Online Library
We are entering the era of personalized medicine in which an individual's genetic makeup
will eventually determine how a doctor can tailor his or her therapy. Therefore, it is becoming …

Multi-omics strategies for personalized and predictive medicine: past, current, and future translational opportunities

Z Ahmed - Emerging topics in life sciences, 2022 - portlandpress.com
Precision medicine is driven by the paradigm shift of empowering clinicians to predict the
most appropriate course of action for patients with complex diseases and improve routine …

[HTML][HTML] Analytical considerations of stable isotope labelling in lipidomics

A Triebl, MR Wenk - Biomolecules, 2018 - mdpi.com
Over the last two decades, lipids have come to be understood as far more than merely
components of cellular membranes and forms of energy storage, and are now also being …

Retention Time Alignment for Protein Turnover Studies Using Heavy Water Metabolic Labeling

HM Deberneh, RG Sadygov - Journal of proteome research, 2023 - ACS Publications
Retention time (RT) alignment has been important for robust protein identification and
quantification in proteomics. In data-dependent acquisition mode, whereby the precursor …

Enzymes as parts in need of replacement–and how to extend their working life

ND Tivendale, AD Hanson, CS Henry… - Trends in plant …, 2020 - cell.com
Enzymes catalyze reactions in vivo at different rates and each enzyme molecule has a
lifetime limit before it is degraded and replaced to enable catalysis to continue. Considering …

[HTML][HTML] Developing sustainable software solutions for bioinformatics by the “Butterfly” paradigm

Z Ahmed, S Zeeshan, T Dandekar - F1000Research, 2014 - ncbi.nlm.nih.gov
Software design and sustainable software engineering are essential for the long-term
development of bioinformatics software. Typical challenges in an academic environment are …

'Isotopo'a database application for facile analysis and management of mass isotopomer data

Z Ahmed, S Zeeshan, C Huber, M Hensel… - Database, 2014 - academic.oup.com
The composition of stable-isotope labelled isotopologues/isotopomers in metabolic products
can be measured by mass spectrometry and supports the analysis of pathways and fluxes …