The paper reviews basic aspects of the biology of Trypanosoma cruzi emphasizing the
following topics:(a) developmental stages of the life cycle in the vertebrate and invertebrate …

Publisher Summary Advances in the understanding of the formation, structure, and
chemistry of the mammalian kinetochore and its associated fiber are summarized in the …

Publisher Summary Among the protozoa of the Trypanosomatidae family, a large number of
species represent agents of diseases, such as Chagas' disease. This chapter reviews some …

Trypanosomatid protozoa provide amazingly fertile ground for the discovery of novel
molecular phenomena such as RNA editing (102), trans-splicing (16), and bent DNA (77) …

The structural basis of mitosis, spindle organisation and chromosome segregation, in the
unicellular parasite Trypanosoma brucei is poorly understood. Here, using …

We have used specific monoclonal antibodies to facilitate a study of acetylated and
tyrosinated α-tubulin in the microtubule (MT) arrays in the Trypanosoma brucei cell …

Chromosome segregation in eukaryotes is driven by the kinetochore, a macromolecular
complex that connects centromeric DNA to microtubules of the spindle apparatus …

Faithful transmission of genetic material is essential for the survival of all organisms.
Eukaryotic chromosome segregation is driven by the kinetochore that assembles onto …

The present review addresses basic aspects of the biology of the pathogenic protozoa
Trypanosoma cruzi and some comparative information of Trypanosoma brucei. Like …

Trypanosomes are ancient eukaryotic parasites in which the protein-coding genes,
organized in large polycistronic clusters on both strands, are transcribed from as yet …