Radiation oncology in the era of precision medicine

M Baumann, M Krause, J Overgaard, J Debus… - Nature Reviews …, 2016 - nature.com
Technological advances and clinical research over the past few decades have given
radiation oncologists the capability to personalize treatments for accurate delivery of …

Adaptive radiation therapy in the treatment of lung cancer: An overview of the current state of the field

H Piperdi, D Portal, SS Neibart, NJ Yue… - Frontiers in …, 2021 - frontiersin.org
Lung cancer treatment is constantly evolving due to technological advances in the delivery
of radiation therapy. Adaptive radiation therapy (ART) allows for modification of a treatment …

European Organization for Research and Treatment of Cancer (EORTC) recommendations for planning and delivery of high-dose, high precision radiotherapy for lung …

D De Ruysscher, C Faivre-Finn, D Moeller… - Radiotherapy and …, 2017 - Elsevier
Purpose To update literature-based recommendations for techniques used in high-precision
thoracic radiotherapy for lung cancer, in both routine practice and clinical trials. Methods A …

Intra thoracic anatomical changes in lung cancer patients during the course of radiotherapy

M Kwint, S Conijn, E Schaake, J Knegjens… - Radiotherapy and …, 2014 - Elsevier
Background and purpose Conebeam-CT (CBCT) guidance is often used for setup
verification of lung cancer patients treated with radiotherapy. The purpose of this study was …

Adaptive radiotherapy for advanced lung cancer ensures target coverage and decreases lung dose

DS Møller, MI Holt, M Alber, M Tvilum, AA Khalil… - Radiotherapy and …, 2016 - Elsevier
Background and purpose Advanced lung cancer patients experience anatomical changes
during radiotherapy. Uncorrected, these may lead to lower tumor dose, but can be corrected …

[HTML][HTML] Evaluation of CBCT based dose calculation in the thorax and pelvis using two generic algorithms

RS Thing, R Nilsson, S Andersson, M Berg, MD Lund - Physica Medica, 2022 - Elsevier
Purpose: This work examines the dosimetric performance of two algorithms creating a
corrected CBCT (corrCBCT) and a virtual CT (vCT) implemented in a commercial treatment …

[HTML][HTML] Advances in the use of motion management and image guidance in radiation therapy treatment for lung cancer

JK Molitoris, T Diwanji, JW Snider III… - Journal of thoracic …, 2018 - ncbi.nlm.nih.gov
The development of advanced radiation technologies, including intensity-modulated
radiation therapy (IMRT), stereotactic body radiation therapy (SBRT) and proton therapy, has …

Adaptation is mandatory for intensity modulated proton therapy of advanced lung cancer to ensure target coverage

L Hoffmann, M Alber, MF Jensen, MI Holt… - Radiotherapy and …, 2017 - Elsevier
Background and purpose Large anatomical changes during radiotherapy are seen for a
large proportion of lung cancer patients. We investigate the applicability of a decision …

New dose constraint reduces radiation-induced fatal pneumonitis in locally advanced non-small cell lung cancer patients treated with intensity-modulated …

AA Khalil, L Hoffmann, DS Moeller, KP Farr… - Acta …, 2015 - Taylor & Francis
Background. Intensity-modulated radiotherapy (IMRT) in locally advanced non-small cell
lung cancer (NSCLC) allows treatment of patients with large tumour volumes, but radiation …

[HTML][HTML] Survival benefits for non-small cell lung cancer patients treated with adaptive radiotherapy

DS Møller, CM Lutz, AA Khalil, M Alber, MI Holt… - Radiotherapy and …, 2022 - Elsevier
Introduction Tumor match and adaptive radiotherapy based on on-treatment imaging
increases the precision of RT. This allows a reduction of treatment volume and …