Overcoming immune evasion in melanoma

K Eddy, S Chen - International journal of molecular sciences, 2020 - mdpi.com
Melanoma is the most aggressive and dangerous form of skin cancer that develops from
transformed melanocytes. It is crucial to identify melanoma at its early stages, in situ, as it is …

Sex and gender disparities in melanoma

M Bellenghi, R Puglisi, G Pontecorvi, A De Feo, A Carè… - Cancers, 2020 - mdpi.com
Worldwide, the total incidence of cutaneous melanoma is higher in men than in women, with
some differences related to ethnicity and age and, above all, sex and gender. Differences …

Bridging the Gap” Everything that Could Have Been Avoided If We Had Applied Gender Medicine, Pharmacogenetics and Personalized Medicine in the Gender …

D Gemmati, K Varani, B Bramanti, R Piva… - International journal of …, 2019 - mdpi.com
Gender medicine is the first step of personalized medicine and patient-centred care, an
essential development to achieve the standard goal of a holistic approach to patients and …

Options of therapeutics and novel delivery systems of drugs for the treatment of melanoma

H Wang, TT Tran, KT Duong, T Nguyen… - Molecular …, 2022 - ACS Publications
Melanoma is one of the most severe cancerous diseases. The cells employ multiple
signaling pathways, such as ERK, HGF/c-MET, WNT, and COX-2 to cause the cell …

Cutaneous melanoma—a long road from experimental models to clinical outcome: a review

D Coricovac, C Dehelean, EA Moaca, I Pinzaru… - International journal of …, 2018 - mdpi.com
Cutaneous melanoma is a complex disorder characterized by an elevated degree of
heterogeneity, features that place it among the most aggressive types of cancer. Although …

Phytochemical Constituents and Derivatives of Cannabis sativa; Bridging the Gap in Melanoma Treatment

E Schanknecht, A Bachari, N Nassar, T Piva… - International Journal of …, 2023 - mdpi.com
Melanoma is deadly, physically impairing, and has ongoing treatment deficiencies. Current
treatment regimens include surgery, targeted kinase inhibitors, immunotherapy, and …

Estrogen receptors and melanoma: a review

E Dika, A Patrizi, M Lambertini, N Manuelpillai… - Cells, 2019 - mdpi.com
In the last three decades cutaneous melanoma has been widely investigated as a steroid
hormone-sensitive cancer. Following this hypothesis, many epidemiological studies have …

Pathology and Molecular Biology of Melanoma

T Timis, JT Bergthorsson, V Greiff, M Cenariu… - Current Issues in …, 2023 - mdpi.com
Almost every death in young patients with an advanced skin tumor is caused by melanoma.
Today, with the help of modern treatments, these patients survive longer or can even …

Behind the scene: exploiting MC1R in skin cancer risk and prevention

M Manganelli, S Guida, A Ferretta, G Pellacani… - Genes, 2021 - mdpi.com
Melanoma and non-melanoma skin cancers (NMSCs) are the most frequent cancers of the
skin in white populations. An increased risk in the development of skin cancers has been …

The gender perspective in cancer research and therapy: novel insights and on-going hypotheses

L Gabriele, M Buoncervello, B Ascione… - Annali Dell'istituto …, 2016 - annali.iss.it
Cancer represents a leading cause of death whose incidence is steadily increasing
worldwide due to the population aging. The Global Health Observatory of the World Health …