The ABCD twin study will elucidate the genetic and environmental contributions to a wide
range of mental and physical health outcomes in children, including substance use, brain …

This review examines the current state of electrophysiological endophenotype research and
recommends best practices that are based on knowledge gleaned from the last decade of …

There are many research approaches to il-luminating and understanding the etiology of
disorders or traits, such as psychopathy and antisocial behavior. Behavior genetic designs …

The current study provides a comprehensive evaluation of critical psychometric properties of
commonly used psychophysiology laboratory tasks/measures within the NIMH RDoC …

In this chapter, we review the current state of knowledge about neural and genetic pathways
that influence three emotional processes:(1) emotional reactivity, which is generating …

Endophenotypes provide a powerful neurobiological platform from which we can
understand the genomic and neural substrates of schizophrenia and other common complex …

Generalized anxiety disorder (GAD) is a prevalent and chronic mental disorder that elicits
widespread functional impairment. Given the high degree of non-response/partial response …

The molecular genetics of panic disorder (PD) with and without agoraphobia (AG) are still
largely unknown and progress is hampered by small sample sizes. We therefore performed …

Startle potentiation is a well‐validated translational measure of negative affect. Startle
potentiation is widely used in clinical and affective science, and there are multiple …

Sensorimotor gating measured by prepulse inhibition (PPI) of the acoustic startle response
(ASR) has been proposed as one of the most promising electrophysiological …