The innate lymphoid cell (ILC) family is composed of natural killer (NK) cells, ILC1, ILC2 and
ILC3, which participate in immune responses to virus, bacteria, parasites and transformed …

Innate lymphoid cells (ILCs) are important for tissue homeostasis and for the initiation of
immune responses. Based on their transcriptional regulation and cytokine profiles, ILCs can …

Although the function of the circulating immune cell compartment has been studied in detail
for decades, limitations in terms of access and cell yields from peripheral tissues have …

The multifaceted organization of the immune system involves not only patrolling
lymphocytes that constantly monitor antigen-presenting cells in secondary lymphoid organs …

γδ T cells are the first T cell lineage to develop in the thymus and take up residence in a
wide variety of tissues where they can provide fast, innate-like sources of effector cytokines …

Early-life cues shape the immune system during adulthood. However, early-life signaling
pathways and their temporal functions are not well understood. Herein, we demonstrate that …

Group 3 innate lymphoid cells (ILC3s) are crucial for the maintenance of host–microbiota
homeostasis in gastrointestinal mucosal tissues. The mechanisms that maintain lineage …

Small intestinal villi are structural and functional units present in higher vertebrates and
uniquely adapted to nutrient absorption. Villus enterocytes are organized in transcriptional …

Innate lymphoid cells (ILCs) are a family of predominantly tissue-resident lymphocytes that
critically orchestrate immunity, inflammation, tolerance and repair at barrier surfaces of the …

The generation of lymphoid tissues during embryogenesis relies on group 3 innate lymphoid
cells (ILC3) displaying lymphoid tissue inducer (LTi) activity and expressing the master …