Accumulating evidence suggests that both the intrauterine environment and growth during
early life can influence the development of chronic noncommunicable diseases, such as …

Growth hormone is widely used clinically to promote growth and anabolism and for other
purposes. Its actions are mediated via the growth hormone receptor, both directly by tyrosine …

Low birth weight (LBW) infants have higher risk of developing insulin resistance and its
comorbidities later in life. The concept of “developmental origins of health and disease” …

Introduction: Among children born small for gestational age, 10–15% fail to catch up and
remain short (SGA-SS). The underlying mechanisms are mostly unknown. We aimed to …

Abstract Background/Aims: We studied the association of low birth weight with ultrasound-
assessed nonalcoholic fatty liver disease (NAFLD) to test the hypothesis that fetal growth …

Approximately 10% of children born small for their gestational age (SGA) fail to show catch-
up growth and may remain short-statured as adults. Despite treatment guidelines for …

Background: Fullterm small-for-gestational-age children (SGAs) are known for their ability to
catch up on growth. Nevertheless, increased risk of growth restriction remains. Evidence on …

Infants with a very low birth weight are at risk of a reduced number of nephrons predisposing
to kidney disorder, hypertension, and metabolic syndrome. Approximately 3% of infants are …

This study aimed to investigate the nationwide growth pattern of infants in Korea according
to the birth-weight group and to analyze the effect of growth on development. A total of …

The optimal dosing of growth hormone (GH) therapy is challenging due to high inter-
individual variability in subcutaneous GH absorption and sensitivity to the drug. Optimal …