A guide to the organ-on-a-chip

CM Leung, P De Haan… - Nature Reviews …, 2022 - nature.com
Abstract Organs-on-chips (OoCs) are systems containing engineered or natural miniature
tissues grown inside microfluidic chips. To better mimic human physiology, the chips are …

Recent trends of microfluidics in food science and technology: Fabrications and applications

R Mu, N Bu, J Pang, L Wang, Y Zhang - Foods, 2022 - mdpi.com
The development of novel materials with microstructures is now a trend in food science and
technology. These microscale materials may be applied across all steps in food …

Droplet-based microfluidics as a platform to design food-grade delivery systems based on the entrapped compound type

JRO Bianchi, LG De la Torre, ALR Costa - Foods, 2023 - mdpi.com
Microfluidic technology has emerged as a powerful tool for several applications, including
chemistry, physics, biology, and engineering. Due to the laminar regime, droplet-based …

The Growing Importance of Three-Dimensional Models and Microphysiological Systems in the Assessment of Mycotoxin Toxicity

V Zingales, MR Esposito, N Torriero, M Taroncher… - Toxins, 2023 - mdpi.com
Current investigations in the field of toxicology mostly rely on 2D cell cultures and animal
models. Although well-accepted, the traditional 2D cell-culture approach has evident …

A facile and green approach toward precise fabrication of silk fibroin-based microfluidic devices using water as etchant

M Zhou, S Wu, F Song, F Chen, F Wang, Q Xia… - European Polymer …, 2022 - Elsevier
Regenerated silk fibroin (RSF) is considered as a superior substrate material for
biocompatible and biodegradable microfluidic devices. However, the manufacture of RSF …

Analysis of chemosensitivity of tumor spheroids exposed to two-dimensional gradient of combination drugs in a hydrogel-based diffusion microfluidic platform

KF Lei, YT Lin, SKR Boreddy, PC Pai - Analytica Chimica Acta, 2024 - Elsevier
Background Liver cancer stands as a leading cause of cancer-related deaths globally,
challenging conventional treatments due to resistance to chemotherapy and targeted …

Microfluidic chip for synergic drugs assay in 3D breast cancer cell

FF Vit, YT Wu, E Fujiwara, HF Carvalho… - Microfluidics and …, 2024 - Springer
Some anticancer treatments may cause Multidrug Resistance (MDR). In these cases, cells
pump the drug out of the intracellular environment, thereby preventing drug effects. Several …

3D cell models in radiobiology: improving the predictive value of in vitro research

F Antonelli - International Journal of Molecular Sciences, 2023 - mdpi.com
Cancer is intrinsically complex, comprising both heterogeneous cellular composition and
extracellular matrix. In vitro cancer research models have been widely used in the past to …

Unlocking Cell Biology Through Development and Application of High-Throughput Microfluidic Cell Sorting

DN Philpott - 2023 - search.proquest.com
Studying biology through a high-throughput lens has enabled many advancements in
academia and healthcare. Yet for cytometry, the analysis and sorting of cells, current tools …

Label free imaging of biological samples using mass spectrometry imaging and Stimulated Raman scattering microscopy

J Majer - 2023 - orca.cardiff.ac.uk
Unlike fluorescence microscopy techniques, label-free imaging techniques avoid
perturbation of the biological environment, which enable the analysis of samples in their …