The Safety and Efficacy of Phage Therapy for Infections in Cardiac and Peripheral Vascular Surgery: A Systematic Review

EA Simpson, CS MacLeod, HJ Stacey, J Nagy… - Antibiotics, 2023 - mdpi.com
New approaches to managing infections in cardiac and peripheral vascular surgery are
required to reduce costs to patients and healthcare providers. Bacteriophage (phage) …

The rise, fall, and resurgence of phage therapy for urinary tract infection

JJ Zulk, KA Patras, AW Maresso - EcoSal Plus, 2024 - Am Soc Microbiol
In the face of rising antimicrobial resistance, bacteriophage therapy, also known as phage
therapy, is seeing a resurgence as a potential treatment for bacterial infections including …

Large-scale genomic survey with deep learning-based method reveals strain-level phage specificity determinants

Y Yang, K Dufault-Thompson, W Yan, T Cai, L Xie… - …, 2024 - academic.oup.com
Background Phage therapy, reemerging as a promising approach to counter antimicrobial-
resistant infections, relies on a comprehensive understanding of the specificity of individual …

Towards Standardization of Phage Susceptibility Testing: The Israeli Phage Therapy Center “Clinical Phage Microbiology”—A Pipeline Proposal

O Yerushalmy, R Braunstein… - Clinical Infectious …, 2023 - academic.oup.com
Using phages as salvage therapy for nonhealing infections is gaining recognition as a
viable solution for patients with such infections. The escalating issue of antibiotic resistance …

Automating Predictive Phage Therapy Pharmacology

ST Abedon - Antibiotics, 2023 - mdpi.com
Viruses that infect as well as often kill bacteria are called bacteriophages, or phages.
Because of their ability to act bactericidally, phages increasingly are being employed …

Phage Therapy for Cardiac Implantable Electronic Devices and Vascular Grafts: A Targeted Literature Review

M Passerini, F Petri, GA Suh - Pathogens, 2024 - mdpi.com
Infections of cardiac implantable electronic devices (CIEDs) and vascular grafts are some of
the most dreaded complications of these otherwise life-saving devices. Many of these …

Phages and phage-borne enzymes as new antibacterial agents

S McCallin, Z Drulis-Kawa, T Ferry, JP Pirnay… - Clinical Microbiology …, 2023 - Elsevier
Background Persistent and resistant infections caused by bacteria are increasing in
numbers and pose a treatment challenge to the medical community and public health …

The Citizen Phage Library: Rapid Isolation of Phages for the Treatment of Antibiotic Resistant Infections in the UK

J Fletcher, R Manley, C Fitch, C Bugert, K Moore… - Microorganisms, 2024 - mdpi.com
Antimicrobial resistance poses one of the greatest threats to global health and there is an
urgent need for new therapeutic options. Phages are viruses that infect and kill bacteria and …

Bacteriophage and antibiotic combination therapy for recurrent Enterococcus faecium bacteremia

ME Stellfox, C Fernandes, RK Shields, G Haidar… - Mbio, 2024 - Am Soc Microbiol
Enterococcus faecium is a member of the human gastrointestinal (GI) microbiota but can
also cause invasive infections, especially in immunocompromised hosts. Enterococci …

Phage therapy: the next frontier in managing periprosthetic joint infection?

JW Kennedy, JD Jones, RMD Meek - The Bone & Joint Journal, 2024 - boneandjoint.org.uk
Periprosthetic joint infection (PJI) is a significant challenge in orthopaedic surgery. Several
operations, protracted treatment, and the high associated morbidity have a very detrimental …