Gastrointestinal-based drug delivery is considered the preferred mode of drug
administration owing to its convenience for patients, which improves adherence. However …

Ionic liquids (ILs) are solvents with salt structures. Typically, they contain organic cations
(ammonium, imidazolium, pyridinium, piperidinium or pyrrolidinium), and halogen …

Artificial intelligence and specifically machine learning applications are nowadays used in a
variety of scientific applications and cutting-edge technologies, where they have a …

Porous organic molecular materials are a subclass of porous solids that are defined by their
modular, molecular structures, and the absence of extended covalent or coordination …

Cocrystals, a long known but understudied class of crystalline solids, have attracted interest
from crystal engineers and pharmaceutical scientists in the past decade and are now an …

Pharmaceutical cocrystals belong to a sub-class of cocrystals wherein one of the
components is a drug molecule (or an active pharmaceutical ingredient, API) and the …

We present new facts about polymorphism based on (i) crystallographic data from the
Cambridge Structural Database (CSD, a database built over 50 years of community …

How do molecules aggregate in solution, and how do these aggregates consolidate
themselves in crystals? What is the relationship between the structure of a molecule and the …

Drugs with low water solubility are predisposed to low and variable oral bioavailability and,
therefore, to variability in clinical response. Despite significant efforts to “design in” …

As small molecule drugs become harder to develop and less cost effective for patient use,
efficient strategies for their property improvement become increasingly important to global …