Cellulases and beyond: the first 70 years of the enzyme producer Trichoderma reesei

RH Bischof, J Ramoni, B Seiboth - Microbial cell factories, 2016 - Springer
More than 70 years ago, the filamentous ascomycete Trichoderma reesei was isolated on
the Solomon Islands due to its ability to degrade and thrive on cellulose containing fabrics …

Factors regulating cellulolytic gene expression in filamentous fungi: an overview

AJ Mattam, YB Chaudhari, HR Velankar - Microbial Cell Factories, 2022 - Springer
The growing demand for biofuels such as bioethanol has led to the need for identifying
alternative feedstock instead of conventional substrates like molasses, etc. Lignocellulosic …

Inducible promoters and functional genomic approaches for the genetic engineering of filamentous fungi

J Kluge, D Terfehr, U Kück - Applied microbiology and biotechnology, 2018 - Springer
In industry, filamentous fungi have a prominent position as producers of economically
relevant primary or secondary metabolites. Particularly, the advent of genetic engineering of …

The transcription factor ACE3 controls cellulase activities and lactose metabolism via two additional regulators in the fungus Trichoderma reesei

J Zhang, Y Chen, C Wu, P Liu, W Wang… - Journal of Biological …, 2019 - ASBMB
Fungi of the genus Trichoderma are a rich source of enzymes, such as cellulases and
hemicellulases, that can degrade lignocellulosic biomass and are therefore of interest for …

Rational engineering of the Trichoderma reesei RUT-C30 strain into an industrially relevant platform for cellulase production

LM Fonseca, LS Parreiras, MT Murakami - Biotechnology for biofuels, 2020 - Springer
Background The path for the development of hypersecreting strains of Trichoderma reesei
capable of producing industrially relevant enzyme titers remains elusive despite over 70 …

[HTML][HTML] Promoter regulation and genetic engineering strategies for enhanced cellulase expression in Trichoderma reesei

M Adnan, X Ma, S Olsson, J Wang, G Liu - Microbiological Research, 2022 - Elsevier
Background Trichoderma reesei has extraordinary potential for high-level protein production
at large scales, and it need to be further explored through genetic engineering tools to …

Understanding the Role of the Master Regulator XYR1 in Trichoderma reesei by Global Transcriptional Analysis

L dos Santos Castro, RG de Paula… - Frontiers in …, 2016 - frontiersin.org
We defined the role of the transcriptional factor—XYR1—in the filamentous fungus
Trichoderma reesei during cellulosic material degradation. In this regard, we performed a …

Production of Industrial Enzymes in Trichoderma reesei

M Paloheimo, T Haarmann, S Mäkinen… - … expression systems in …, 2016 - Springer
Trichoderma reesei (teleomorph Hypocrea jecorina) is one of the two major fungal platforms
for industrial enzyme production, along with Aspergillus sp. Its use derives from its history as …

The Promoter Toolbox for Recombinant Gene Expression in Trichoderma reesei

E Fitz, F Wanka, B Seiboth - Frontiers in bioengineering and …, 2018 - frontiersin.org
The ascomycete Trichoderma reesei is one of the main fungal producers of cellulases and
xylanases based on its high production capacity. Its enzymes are applied in food, feed, and …

Trichoderma – genomes and genomics as treasure troves for research towards biology, biotechnology and agriculture

M Schalamun, M Schmoll - Frontiers in Fungal Biology, 2022 - frontiersin.org
The genus Trichoderma is among the best studied groups of filamentous fungi, largely
because of its high relevance in applications from agriculture to enzyme biosynthesis to …