Copper oxide nanoparticles: In vitro and in vivo toxicity, mechanisms of action and factors influencing their toxicology

H Sajjad, A Sajjad, RT Haya, MM Khan, M Zia - … and Physiology Part C …, 2023 - Elsevier
Abstract Copper oxide nanoparticles (CuO NPs) have received increasing interest due to
their distinctive properties, including small particle size, high surface area, and reactivity …

Copper signalling: causes and consequences

J Kardos, L Héja, Á Simon, I Jablonkai… - Cell Communication and …, 2018 - Springer
Copper-containing enzymes perform fundamental functions by activating dioxygen (O 2) and
therefore allowing chemical energy-transfer for aerobic metabolism. The copper …

[PDF][PDF] Copper and copper nanoparticles toxicity and their impact on basic functions in the body

M Pohanka - Bratisl Lek Listy, 2019 - researchgate.net
Copper is a biogenic metal having multiple functions in basic processes in organisms and it
is common in all kingdoms of life. Limited intake of copper is a problem; however, doses of …

Genetic heterogeneity of motor neuropathies

B Bansagi, H Griffin, RG Whittaker, T Antoniadi… - Neurology, 2017 - AAN Enterprises
Objective: To study the prevalence, molecular cause, and clinical presentation of hereditary
motor neuropathies in a large cohort of patients from the North of England. Methods …

Wilson's disease: facing the challenge of diagnosing a rare disease

A Sánchez-Monteagudo, E Ripollés, M Berenguer… - Biomedicines, 2021 - mdpi.com
Wilson disease (WD) is a rare disorder caused by mutations in ATP7B, which leads to the
defective biliary excretion of copper. The subsequent gradual accumulation of copper in …

Missing heritability of Wilson disease: a search for the uncharacterized mutations

S Roy, S Ghosh, J Ray, K Ray, M Sengupta - Mammalian Genome, 2023 - Springer
Wilson disease (WD), a copper metabolism disorder caused by mutations in ATP7B,
manifests heterogeneous clinical features. Interestingly, in a fraction of clinically diagnosed …

Coumarin–lipoic acid conjugates on silver nanoparticle-supported nanopipettes for in situ dual-mode monitoring of intracellular Cu (II) and potential chemodynamic …

VTTX Ho, H Park, S An, G Kim, NH Ly, SY Lee… - Sensors and Actuators B …, 2021 - Elsevier
Intracellular Cu (II) in the human body is essential to many physiological functions, and its
disruption is connected to several diseases. Synthetic coumarin–lipoic acid (Cou-LA) …

Synthesis of a Novel Unexpected Cu (II)–Thiazolidine Complex—X-ray Structure, Hirshfeld Surface Analysis, and Biological Studies

MS Altowyan, SMSM Khalil, D Al-Wahaib, A Barakat… - Molecules, 2022 - mdpi.com
An unexpected trinuclear Cu (II)–thiazolidine complex has been synthesized by mixing
CuCl2· 2H2O with the Schiff base ligand, 1-(((4, 5-dihydrothiazol-2-yl) ethylidene) …

Neuropathology and pathogenesis of extrapyramidal movement disorders: a critical update. II. Hyperkinetic disorders

KA Jellinger - Journal of Neural Transmission, 2019 - Springer
Extrapyramidal movement disorders comprise hypokinetic-rigid and hyperkinetic or mixed
forms, most of them originating from dysfunction of the basal ganglia (BG) and their …

Recent endeavors on molecular imaging for mapping metals in biology

J Gao, Y Chen, Z Guo, W He - Biophysics Reports, 2020 - Springer
Transition metals such as zinc, copper and iron play vital roles in maintaining physiological
functions and homeostasis of living systems. Molecular imaging, including two-photon …