There is an urgent need for novel biomarkers that can be used to improve the diagnosis,
predict the disease progression, improve our understanding of the pathology or serve as …

The physiological and biophysical knowledge base for interpretations of cerebrospinal fluid
(CSF) data and reference ranges are essential for the clinical pathologist and neurochemist …

The integration of quantitative trait loci (QTLs) with disease genome-wide association
studies (GWASs) has proven successful in prioritizing candidate genes at disease …

As the body fluid that directly interchanges with the extracellular fluid of the central nervous
system (CNS), cerebrospinal fluid (CSF) serves as a rich source for CNS-related disease …

Lipid nanoparticles (LNPs) have successfully entered the clinic for the delivery of mRNA-and
siRNA-based therapeutics, most recently as vaccines for COVID-19. Nevertheless, there is a …

The integration of quantitative trait loci (QTL) with disease genome-wide association studies
(GWAS) has proven successful at prioritizing candidate genes at disease-associated loci …

In this study, the human cerebrospinal fluid (CSF) proteome was mapped using three
different strategies prior to Orbitrap LC-MS/MS analysis: SDS-PAGE and mixed mode …

Purpose This study is part of a larger effort aiming to expand the knowledge of brain‐
enriched proteins in human cerebrospinal fluid (CSF) and to provide novel insight into the …

The analysis of intrathecal IgG, IgA and IgM synthesis in cerebrospinal fluid (CSF) and
evaluation in combined quotient diagrams provides disease-related patterns. The …

Background: Cerebrospinal fluid (CSF) kappa free light chains (KFLC) are gaining
increasing interest as markers of intrathecal immunoglobulin synthesis. The main aim of this …