Transcription factor networks in cellular quiescence

M Mitra, SL Batista, HA Coller - Nature Cell Biology, 2025 - nature.com
Many of the cells in mammalian tissues are in a reversible quiescent state; they are not
dividing, but retain the ability to proliferate in response to extracellular signals. Quiescence …

Mapping Cell Atlases at the Single‐Cell Level

F Ye, J Wang, J Li, Y Mei, G Guo - Advanced Science, 2024 - Wiley Online Library
Recent advancements in single‐cell technologies have led to rapid developments in the
construction of cell atlases. These atlases have the potential to provide detailed information …

Skeletal muscle regeneration failure in ischemic-damaged limbs is associated with pro-inflammatory macrophages and premature differentiation of satellite cells

KW Southerland, Y Xu, DT Peters, X Lin, X Wei… - Genome Medicine, 2023 - Springer
Background Chronic limb-threatening ischemia (CLTI), a severe manifestation of peripheral
arterial disease (PAD), is associated with a 1-year limb amputation rate of approximately 15 …

Glycosaminoglycan modifications of betaglycan regulate ectodomain shedding to fine-tune TGF-β signaling responses in ovarian cancer

AS Choi, LM Jenkins-Lane, W Barton, A Kumari… - Cell Communication and …, 2024 - Springer
In pathologies including cancer, aberrant Transforming Growth Factor-β (TGF-β) signaling
exerts profound tumor intrinsic and extrinsic consequences. Intense clinical endeavors are …

Single-nucleus transcriptomic analysis reveals the regulatory circuitry of myofiber XBP1 during regenerative myogenesis

AS Joshi, MB Castillo, MT da Silva, AT Vuong… - iScience, 2024 - cell.com
Endoplasmic reticulum (ER) stress-induced unfolded protein response (UPR) is activated in
skeletal muscle under multiple conditions. However, the role of the UPR in the regulation of …

Beyond the bulk: overview and novel insights into the dynamics of muscle satellite cells during muscle regeneration

WS Byun, J Lee, JH Baek - Inflammation and Regeneration, 2024 - Springer
Skeletal muscle possesses remarkable regenerative capabilities, fully recovering within a
month following severe acute damage. Central to this process are muscle satellite cells …

[HTML][HTML] A Latent Activated Olfactory Stem Cell State Revealed by Single Cell Transcriptomic and Epigenomic Profiling

K Van den Berge, HJ Chou, D Kunda, D Risso, K Street… - bioRxiv, 2023 - ncbi.nlm.nih.gov
The olfactory epithelium is one of the few regions of the nervous system that sustains
neurogenesis throughout life. Its experimental accessibility makes it especially tractable for …

Chromatin organization of muscle stem cell.

P Santarelli, V Rosti, M Vivo… - Current Topics in …, 2024 - europepmc.org
The proper functioning of skeletal muscles is essential throughout life. A crucial crosstalk
between the environment and several cellular mechanisms allows striated muscles to …