MYC: a multipurpose oncogene with prognostic and therapeutic implications in blood malignancies

SE Ahmadi, S Rahimi, B Zarandi, R Chegeni… - Journal of hematology & …, 2021 - Springer
MYC oncogene is a transcription factor with a wide array of functions affecting cellular
activities such as cell cycle, apoptosis, DNA damage response, and hematopoiesis. Due to …

EDC-2: the Endocrine Society's second scientific statement on endocrine-disrupting chemicals

AC Gore, VA Chappell, SE Fenton, JA Flaws… - Endocrine …, 2015 - academic.oup.com
Abstract The Endocrine Society's first Scientific Statement in 2009 provided a wake-up call to
the scientific community about how environmental endocrine-disrupting chemicals (EDCs) …

Physiologic events of embryo implantation and decidualization in human and non-human primates

MA Ochoa-Bernal, AT Fazleabas - International journal of molecular …, 2020 - mdpi.com
Reproduction is a fundamental process for the preservation of the human species. This
process requires a sequence of orchestrated events that are necessary for a successful …

The complexity of miRNA-mediated repression

A Wilczynska, M Bushell - Cell Death & Differentiation, 2015 - nature.com
Since their discovery 20 years ago, miRNAs have attracted much attention from all areas of
biology. These short (∼ 22 nt) non-coding RNA molecules are highly conserved in evolution …

How does epigenetics influence the course of evolution?

A Ashe, V Colot, BP Oldroyd - … transactions of the …, 2021 - royalsocietypublishing.org
Epigenetics is the study of changes in gene activity that can be transmitted through cell
divisions but cannot be explained by changes in the DNA sequence. Epigenetic …

Environmental epigenetics and its implication on disease risk and health outcomes

SM Ho, A Johnson, P Tarapore, V Janakiram… - ILAR …, 2012 - academic.oup.com
This review focuses on how environmental factors through epigenetics modify disease risk
and health outcomes. Major epigenetic events, such as histone modifications, DNA …

Reproducibility of quantitative RT-PCR array in miRNA expression profiling and comparison with microarray analysis

Y Chen, JAL Gelfond, LM McManus, PK Shireman - BMC genomics, 2009 - Springer
Background MicroRNAs (miRNAs) have critical functions in various biological processes.
MiRNA profiling is an important tool for the identification of differentially expressed miRNAs …

[HTML][HTML] Epigenetics meets endocrinology

X Zhang, SM Ho - Journal of molecular endocrinology, 2011 - ncbi.nlm.nih.gov
Although genetics determines endocrine phenotypes, it cannot fully explain the great
variability and reversibility of the system in response to environmental changes. Evidence …

miRNA in the regulation of skeletal muscle adaptation to acute endurance exercise in C57Bl/6J male mice

A Safdar, A Abadi, M Akhtar, BP Hettinga… - PloS one, 2009 - journals.plos.org
MicroRNAs (miRNAs) are evolutionarily conserved small non-coding RNA species involved
in post-transcriptional gene regulation. In vitro studies have identified a small number of …

Beyond cortex: The evolution of the human brain.

R Chin, SWC Chang, AJ Holmes - Psychological Review, 2023 - psycnet.apa.org
Human evolution has been marked by a striking increase in total brain volume relative to
body size. While a prominent and characteristic feature of this volumetric shift has been the …