[HTML][HTML] Neuroinflammation in vascular cognitive impairment and dementia: current evidence, advances, and prospects

Z Tian, X Ji, J Liu - International Journal of Molecular Sciences, 2022 - mdpi.com
Vascular cognitive impairment and dementia (VCID) is a major heterogeneous brain
disease caused by multiple factors, and it is the second most common type of dementia in …

Chronic cerebral hypoperfusion: a key mechanism leading to vascular cognitive impairment and dementia. Closing the translational gap between rodent models and …

J Duncombe, A Kitamura, Y Hase, M Ihara… - Clinical …, 2017 - portlandpress.com
Increasing evidence suggests that vascular risk factors contribute to neurodegeneration,
cognitive impairment and dementia. While there is considerable overlap between features of …

Models and mechanisms of vascular dementia

P Venkat, M Chopp, J Chen - Experimental neurology, 2015 - Elsevier
Vascular dementia (VaD) is the second leading form of dementia after Alzheimer's disease
(AD) plaguing the elderly population. VaD is a progressive disease caused by reduced …

White matter degeneration in vascular and other ageing‐related dementias

Y Hase, K Horsburgh, M Ihara… - Journal of …, 2018 - Wiley Online Library
Advances in neuroimaging have enabled greater understanding of the progression of
cerebral degenerative processes associated with ageing‐related dementias. Leukoaraiosis …

Consensus statement for diagnosis of subcortical small vessel disease

GA Rosenberg, A Wallin, JM Wardlaw… - Journal of Cerebral …, 2016 - journals.sagepub.com
Vascular cognitive impairment (VCI) is the diagnostic term used to describe a
heterogeneous group of sporadic and hereditary diseases of the large and small blood …

[HTML][HTML] Dysfunction of cerebrovascular endothelial cells: prelude to vascular dementia

F Wang, Y Cao, L Ma, H Pei, WD Rausch… - Frontiers in aging …, 2018 - frontiersin.org
Vascular dementia (VaD) is the second most common type of dementia after Alzheimer's
disease (AD), characterized by progressive cognitive impairment, memory loss, and thinking …

Matrix metalloproteinases as therapeutic targets for stroke

Y Yang, GA Rosenberg - Brain research, 2015 - Elsevier
Matrix metalloproteinases (MMPs) are important in injury and recovery in ischemic injury.
They are proteolytic enzymes that degrade all components of the extracellular matrix (ECM) …

Alzheimer's disease: the link between amyloid-β and neurovascular dysfunction

E Solis Jr, KN Hascup… - Journal of Alzheimer's …, 2020 - content.iospress.com
While prevailing evidence supports that the amyloid cascade hypothesis is a key component
of Alzheimer's disease (AD) pathology, many recent studies indicate that the vascular …

Vascular dementia: different forms of vessel disorders contribute to the development of dementia in the elderly brain

DR Thal, LT Grinberg, J Attems - Experimental gerontology, 2012 - Elsevier
The diagnosis of vascular dementia (VaD) describes a group of various vessel disorders
with different types of vascular lesions that finally contribute to the development of dementia …

Molecular mechanisms of vascular dementia: what can be learned from animal models of chronic cerebral hypoperfusion?

SQ Du, XR Wang, LY Xiao, JF Tu, W Zhu, T He… - Molecular …, 2017 - Springer
Vascular dementia (VD) is defined as a progressive neurodegenerative disease of cognitive
decline, attributable to cerebrovascular factors. Numerous studies have demonstrated that …