[HTML][HTML] Genkwanin: An emerging natural compound with multifaceted pharmacological effects

N El Menyiy, S Aboulaghras, S Bakrim… - Biomedicine & …, 2023 - Elsevier
Plant bioactive molecules could play key preventive and therapeutic roles in chronological
aging and the pathogenesis of many chronic diseases, often accompanied by increased …

Interactions with microbial proteins driving the antibacterial activity of flavonoids

G Donadio, F Mensitieri, V Santoro, V Parisi… - Pharmaceutics, 2021 - mdpi.com
Flavonoids are among the most abundant natural bioactive compounds produced by plants.
Many different activities have been reported for these secondary metabolites against …

Anti-bacterial, anti-biofilm and anti-quorum sensing activities of honey: A review

B Khataybeh, Z Jaradat, Q Ababneh - Journal of Ethnopharmacology, 2023 - Elsevier
Ethnopharmacological relevance Man has used honey to treat diseases since ancient times,
perhaps even before the history of medicine itself. Several civilizations have utilized natural …

Phenolic compounds in bacterial inactivation: a perspective from Brazil

AC Kauffmann, VS Castro - Antibiotics, 2023 - mdpi.com
Phenolic compounds are natural substances that are produced through the secondary
metabolism of plants, fungi, and bacteria, in addition to being produced by chemical …

A comprehensive review on pharmacology of efflux pumps and their inhibitors in antibiotic resistance

V Thakur, A Uniyal, V Tiwari - European Journal of Pharmacology, 2021 - Elsevier
The potential for the build-up of resistance to a particular antibiotic endangers its therapeutic
application over time. In recent decades, antibiotic resistance has become one of the most …

The current state of knowledge in biological properties of cirsimaritin

T Benali, I Jaouadi, R Ghchime, N El Omari, K Harboul… - Antioxidants, 2022 - mdpi.com
The search for natural plant-based products as new pharmacological alternatives to treat
various human pathologies has taken on great importance for researchers and research …

Efflux pump inhibitors: a novel approach to combat efflux-mediated drug resistance in bacteria

Y Wang, H Venter, S Ma - Current drug targets, 2016 - ingentaconnect.com
The increasing multi-drug resistance has become a major threat to the public health.
Overexpression of multidrug efflux pumps is one of the major mechanisms of drug resistance …

Effect of Carvacrol and Thymol on NorA efflux pump inhibition in multidrug-resistant (MDR) Staphylococcus aureus strains

CR dos Santos Barbosa, JR Scherf… - Journal of Bioenergetics …, 2021 - Springer
Undue exposure to antimicrobials has led to the acquisition and development of
sophisticated bacterial resistance mechanisms, such as efflux pumps, which are able to …

Methoxylated flavones: occurrence, importance, biosynthesis

A Berim, DR Gang - Phytochemistry reviews, 2016 - Springer
Lipophilic flavones with several methoxyl residues occur in various clades of land plants,
from liverworts to core eudicots. Their chemodiversity is mediated by the manifold …

Inhibition of Drug Efflux Pumps in Staphylococcus Aureus: Current Status of Potentiating Existing Antibiotics

BD Schindler, P Jacinto, GW Kaatz - Future microbiology, 2013 - Taylor & Francis
The emergence of multidrug-resistant Staphylococcus aureus coupled with a declining
output of new antibiotic treatment options from the pharmaceutical industry is a growing …