Cochrane, Maria Crespo Leiro, Anne Dipchand, Brian Feingold, Kathleen Grady, Edward
Horn, Maryl Johnson, Donna Mancini, Sean Pinney, Heather Ross, Kari Wujcik, Andreas …

Background Heart failure (HF) is a significant cause of mortality in children and therefore
there is interest in understanding the optimal way to support these children with Ventricular …

As the use of mechanical circulatory support has increased in volume and complexity,
anticoagulation remains an intricate component of a patient's pharmacotherapy plan …

Background Previous studies have demonstrated that children in the United States who
were of racial and ethnic minorities have inferior waitlist and post-heart transplant (HT) …

BACKGROUND The Berlin Heart EXCOR Pediatric (EXCOR) ventricular assist device (VAD)
was introduced in North America nearly 2 decades ago. The EXCOR was approved under …

Background The use of ventricular assist devices (VADs) as a bridge-to-transplant in
patients with single-ventricle physiology post–stage one palliation has been associated with …

There is a paucity of data regarding the use of direct thrombin inhibitors such as bivalirudin
for children on extracorporeal life support (ECLS). We sought to compare the outcomes of …

We retrospectively compared anticoagulation with heparin and bivalirudin for 32
consecutive children under 18 years old during extracorporeal membrane oxygenation …

Objectives: Objective of this study was to determine if bivalirudin resulted in less circuit
interventions than unfractionated heparin. A secondary objective was to examine …

Objectives Activated partial thromboplastin time (aPTT) is the primary test used to monitor
intravenous (IV) direct thrombin inhibitors (DTIs) but has many limitations. The plasma …