Advances in kidney preservation techniques and their application in clinical practice

SA Hosgood, RJ Brown, ML Nicholson - Transplantation, 2021 - journals.lww.com
The use of cold preservation solutions to rapidly flush and cool the kidney followed by static
cold storage in ice has been the standard kidney preservation technique for the last 50 y …

Outcomes of kidney perfusion techniques in transplantation from deceased donors: a systematic review and meta-analysis

AS Ghoneima, RX Sousa Da Silva, MA Gosteli… - Journal of Clinical …, 2023 - mdpi.com
The high demand for organs in kidney transplantation and the expansion of the donor pool
have led to the widespread implementation of machine perfusion technologies. In this study …

The effects of oxygenation on ex vivo kidneys undergoing hypothermic machine perfusion

K Patel, TB Smith, DAH Neil, A Thakker… - …, 2019 - journals.lww.com
Background Supplemental oxygenation of the standard hypothermic machine perfusion
(HMP) circuit has the potential to invoke favorable changes in metabolism, optimizing …

Hypothermic machine perfusion versus static cold storage in deceased donor kidney transplantation: a systematic review and meta‐analysis of randomized controlled …

P Peng, Z Ding, Y He, J Zhang, X Wang… - Artificial organs, 2019 - Wiley Online Library
Static cold storage (SCS) and hypothermic machine perfusion (HMP) are two primary
options for renal allograft preservation. Compared with SCS, HMP decreased the incidence …

[HTML][HTML] Hypothermic, oxygenated perfusion (HOPE) provides cardioprotection via succinate oxidation prior to normothermic perfusion in a rat model of donation after …

RK Wyss, NM Carmona, M Arnold, A Segiser… - American Journal of …, 2021 - Elsevier
In donation after circulatory death (DCD), cardiac grafts are subjected to warm ischemia in
situ, prior to a brief period of cold, static storage (CSS) at procurement, and ex situ …

Novel Organ Perfusion and Preservation Strategies in Transplantation–Where Are We Going in the United Kingdom?

S O'Neill, S Srinivasa, CJ Callaghan, CJE Watson… - …, 2020 - journals.lww.com
This review article focuses on current clinical outcomes with novel perfusion strategies in
organ transplantation. Broadly, these approaches can be divided into in situ regional …

Hypothermic oxygenated perfusion: a simple and effective method to modulate the immune response in kidney transplantation

P Kron, A Schlegel, X Muller, A Gaspert… - …, 2019 - journals.lww.com
Background. Hypothermic oxygenated perfusion (HOPE) has been shown to protect liver
recipients from acute rejection in an allogeneic model of liver transplantation in rats. Here …

[HTML][HTML] Kidney transplant outcome of expanded criteria donors after circulatory death

PB Monteoliva, D Redondo-Pachón, EM García… - Nefrología (English …, 2022 - Elsevier
The increase in the number of patients on the kidney transplant waiting list has led to an
attempt to increase the number of potential donors by incorporating candidates that …

Cold pulsatile machine perfusion versus static cold storage for kidneys donated after circulatory death: a multicenter randomized controlled trial

DM Summers, N Ahmad, LV Randle… - …, 2020 - journals.lww.com
Background. The benefits of cold pulsatile machine perfusion (MP) for the storage and
transportation of kidneys donated after circulatory death are disputed. We conducted a UK …

Cold pulsatile machine perfusion versus static cold storage in kidney transplantation: a single centre experience

MI Bellini, S Charalampidis, PE Herbert… - BioMed research …, 2019 - Wiley Online Library
Introduction. We present our experience with hypothermic machine perfusion (HMP) versus
cold storage (CS) in relation to kidney transplant outcomes. Methods. Retrospective analysis …