Bacterial plasminogen activators and receptors

K Lähteenmäki, P Kuusela… - FEMS microbiology …, 2001 - academic.oup.com
Invasive bacterial pathogens intervene at various stages and by various mechanisms with
the mammalian plasminogen/plasmin system. A vast number of pathogens express plasmin …

Streptokinase—a clinically useful thrombolytic agent

A Banerjee, Y Chisti, UC Banerjee - Biotechnology advances, 2004 - Elsevier
A failure of hemostasis and consequent formation of blood clots in the circulatory system can
produce severe outcomes such as stroke and myocardial infraction. Pathological …

Activity assessment of microbial fibrinolytic enzymes

E Kotb - Applied microbiology and biotechnology, 2013 - Springer
Conversion of fibrinogen to fibrin inside blood vessels results in thrombosis, leading to
myocardial infarction and other cardiovascular diseases. In general, there are four therapy …

[HTML][HTML] Structural biology and protein engineering of thrombolytics

J Mican, M Toul, D Bednar, J Damborsky - Computational and structural …, 2019 - Elsevier
Myocardial infarction and ischemic stroke are the most frequent causes of death or disability
worldwide. Due to their ability to dissolve blood clots, the thrombolytics are frequently used …

Streptokinase—the drug of choice for thrombolytic therapy

A Kunamneni, TTA Abdelghani, P Ellaiah - Journal of thrombosis and …, 2007 - Springer
Thrombosis, the blockage of blood vessels with clots, can lead to acute myocardial infarction
and ischemic stroke, both leading causes of death. Other than surgical interventions to …

Characterization of Group B streptococcal glyceraldehyde-3-phosphate dehydrogenase: surface localization, enzymatic activity, and protein protein interactions

KN Seifert, WP McArthur, AS Bleiweis… - Canadian journal of …, 2003 - cdnsciencepub.com
La caractérisation des antigènes de surface des streptocoques du groupe B sérotype III
(SGB) a révélé l'existence d'une protéine migrant à une M r~ 173 500 sur un gel de SDS …

Isolation, production, purification, assay and characterization of fibrinolytic enzymes (Nattokinase, Streptokinase and Urokinase) from bacterial sources

R Dubey, J Kumar, D Agrawala, T Char… - African Journal of …, 2011 - ajol.info
Abstract Nattokinase, Streptokinase and Urokinase are novel fibrinolytic enzymes which are
isolated from Bacillus subtilis, β-haemolytic Streptococci and urine sample. The fibrinolytic …

[图书][B] Fibrinolytic bacterial enzymes with thrombolytic activity

E Kotb, E Kotb - 2012 - Springer
This book describes the fibrinolytic enzymes of microbial origin that are able to dissolve
endogenous thrombi in vivo. The fibrinolytic enzyme streptokinase for example, is produced …

Streptokinase: an efficient enzyme in cardiac medicine

MA Zia - Protein and Peptide Letters, 2020 - ingentaconnect.com
An imbalance in oxygen supply to cardiac tissues or formation of thrombus leads to
deleterious results like pulmonary embolism, coronary heart disease and acute cardiac …

Structure-function analysis of the streptokinase amino terminus (residues 1–59)

LV Mundada, M Prorok, ME DeFord, M Figuera… - Journal of biological …, 2003 - ASBMB
Streptokinase (SK) binds to plasminogen (Pg) to form a complex that converts substrate Pg
to plasmin. Residues 1–59 of SK regulate its capacity to induce an active site in bound Pg by …