A failure of hemostasis and consequent formation of blood clots in the circulatory system can produce severe outcomes such as stroke and myocardial infraction. Pathological …
E Kotb - Applied microbiology and biotechnology, 2013 - Springer
Conversion of fibrinogen to fibrin inside blood vessels results in thrombosis, leading to myocardial infarction and other cardiovascular diseases. In general, there are four therapy …
J Mican, M Toul, D Bednar, J Damborsky - Computational and structural …, 2019 - Elsevier
Myocardial infarction and ischemic stroke are the most frequent causes of death or disability worldwide. Due to their ability to dissolve blood clots, the thrombolytics are frequently used …
Thrombosis, the blockage of blood vessels with clots, can lead to acute myocardial infarction and ischemic stroke, both leading causes of death. Other than surgical interventions to …
KN Seifert, WP McArthur, AS Bleiweis… - Canadian journal of …, 2003 - cdnsciencepub.com
La caractérisation des antigènes de surface des streptocoques du groupe B sérotype III (SGB) a révélé l'existence d'une protéine migrant à une M r~ 173 500 sur un gel de SDS …
R Dubey, J Kumar, D Agrawala, T Char… - African Journal of …, 2011 - ajol.info
Abstract Nattokinase, Streptokinase and Urokinase are novel fibrinolytic enzymes which are isolated from Bacillus subtilis, β-haemolytic Streptococci and urine sample. The fibrinolytic …
This book describes the fibrinolytic enzymes of microbial origin that are able to dissolve endogenous thrombi in vivo. The fibrinolytic enzyme streptokinase for example, is produced …
MA Zia - Protein and Peptide Letters, 2020 - ingentaconnect.com
An imbalance in oxygen supply to cardiac tissues or formation of thrombus leads to deleterious results like pulmonary embolism, coronary heart disease and acute cardiac …
LV Mundada, M Prorok, ME DeFord, M Figuera… - Journal of biological …, 2003 - ASBMB
Streptokinase (SK) binds to plasminogen (Pg) to form a complex that converts substrate Pg to plasmin. Residues 1–59 of SK regulate its capacity to induce an active site in bound Pg by …