ISFETs in CMOS and emergent trends in instrumentation: A review

N Moser, TS Lande, C Toumazou… - IEEE Sensors …, 2016 - ieeexplore.ieee.org
Over the past decade, ion-sensitive field-effect transistors (ISFETs) have played a major role
in enabling the fabrication of fully integrated CMOS-based chemical sensing systems. This …

Recent advances of field-effect transistor technology for infectious diseases

A Panahi, D Sadighbayan, S Forouhi, E Ghafar-Zadeh - Biosensors, 2021 - mdpi.com
Field-effect transistor (FET) biosensors have been intensively researched toward label-free
biomolecule sensing for different disease screening applications. High sensitivity, incredible …

ISFET arrays for lab-on-chip technology: A review

N Moser, L Keeble… - 2019 26th IEEE …, 2019 - ieeexplore.ieee.org
This paper reviews the field of ISFET arrays for Lab-on-Chip applications from the early age
of ISFET instrumentation to the current state-of-the-art. We provide an overview of the last …

Ultrafast large-scale chemical sensing with CMOS ISFETs: A level-crossing time-domain approach

Y Liu, TG Constandinou… - IEEE Transactions on …, 2019 - ieeexplore.ieee.org
The introduction of large-scale chemical sensing systems in CMOS which integrate millions
of ISFET sensors have allowed applications such as DNA sequencing and fine-pixel …

A new era of semiconductor genetics using ion-sensitive field-effect transistors: the gene-sensitive integrated cell

C Toumazou, TSLK Thay… - … Transactions of the …, 2014 - royalsocietypublishing.org
Semiconductor genetics is now disrupting the field of healthcare owing to the rapid
parallelization and scaling of DNA sensing using ion-sensitive field-effect transistors …

A novel pH-to-time ISFET pixel architecture with offset compensation

N Moser, TS Lande, P Georgiou - 2015 IEEE International …, 2015 - ieeexplore.ieee.org
A novel pixel architecture is presented to be part of a pH-based DNA microarray using
ISFETs as chemical sensors. The design, based on APS architectures, performs pulse width …

A 32× 32 ISFET array with in-pixel digitisation and column-wise TDC for ultra-fast chemical sensing

Y Liu, TG Constandinou… - 2019 IEEE International …, 2019 - ieeexplore.ieee.org
This paper presents a 32× 32 ISFET sensing array with in-pixel digitisation for pH sensing.
The in-pixel digitisation is achieved using an inverter-based sensing pixel that is controlled …

A highly sensitive ISFET using pH-to-current conversion for real-time DNA sequencing

MM Uzzal, P Zarkesh-Ha, JS Edwards… - 2014 27th IEEE …, 2014 - ieeexplore.ieee.org
In this paper we present a new sensing concept for ISFET based on pH-to-current
conversion. The high sensitivity of our proposed pH-to-current ISFET is achieved by …

Design and analysis of scalability in current-mode analog-to-time converter for an energy-efficient and high-resolution CMOS biosensor array

K Ikeda, A Kobayashi, K Nakazato… - IEICE Transactions on …, 2017 - search.ieice.org
High-resolution bio-imaging is a key component for the advancement of life science. CMOS
electronics is one of the promising candidates for emerging high-resolution devices because …

Charge-conserved analog-to-time converter for a large-scale CMOS biosensor array

M Takihi, K Niitsu, K Nakazato - 2014 IEEE International …, 2014 - ieeexplore.ieee.org
In a large-scale time-domain sensor array, propagation of the pulse voltage causes
considerable pulse distortion due to a large bitline capacitance. This work demonstrates a …