Nitric oxide (NO) is one of the most pleiotropic signaling molecules at systemic and cellular
levels, participating in vascular tone regulation, cellular respiration, proliferation, apoptosis …

Persistence of pulmonary hypertension leading to respiratory failure in the neonate has
been recognized for 40 years since its original description by Gersony and colleagues 1 in …

Intrauterine growth restriction (IUGR) increases the risk for bronchopulmonary dysplasia
(BPD). Abnormal lung structure has been noted in animal models of IUGR, but whether …

The main cause of pulmonary hypertension in newborn babies results from the failure of the
pulmonary circulation to dilate at birth, termed 'persistent pulmonary hypertension of the …

Prevention or treatment of lung diseases caused by the failure to form, or destruction of,
existing alveoli, as observed in infants with bronchopulmonary dysplasia and adults with …

Late-outgrowth endothelial colony-forming cells (ECFCs), a type of circulating endothelial
progenitor cell (EPC), may contribute to pulmonary angiogenesis during development. Cord …

Vitamin D (vit D) has anti-inflammatory properties and modulates lung growth, but whether
vit D can prevent lung injury after exposure to antenatal inflammation is unknown. We …

Autophagy is a process for cells to degrade proteins or entire organelles to maintain a
balance in the synthesis, degradation, and subsequent recycling of cellular products …

Exposure of preterm infants to hyperoxia impairs vascular growth, contributing to the
development of bronchopulmonary dysplasia and retinopathy of prematurity. Disruption of …

Pulmonary arterial hypertension (PAH) is a devastating cardiopulmonary disorder
characterized by pulmonary arterial remodeling mainly due to excess cellular proliferation …