Background: Limb muscle dysfunction is prevalent in chronic obstructive pulmonary disease
(COPD) and it has important clinical implications, such as reduced exercise tolerance …

Abstract Thioredoxins (Trxs), glutaredoxins (Grxs), and peroxiredoxins (Prxs) have been
characterized as electron donors, guards of the intracellular redox state, and “antioxidants” …

Pharmacological sodium nitrate supplementation has been reported to reduce the O 2 cost
of submaximal exercise in humans. In this study, we hypothesized that dietary …

The purpose of this study was to elucidate the mechanistic bases for the reported reduction
in the O2 cost of exercise following short-term dietary nitrate (NO3−) supplementation. In a …

Spirulina is free‐floating filamentous microalgae growing in alkaline water bodies. With its
high nutritional value, Spirulina has been consumed as food for centuries in Central Africa. It …

Ashwagandha (Withania somnifera) is considered a potent adaptogen and anti-stress agent
that could have some potential to improve physical performance. This preferred reporting …

The observation that muscular exercise is associated with oxidative stress in humans was
first reported over 30years ago. Since this initial report, numerous studies have confirmed …

The aim of this review was to examine the mechanisms by which physical activity and
inactivity modify muscle fatigue. It is well known that acute or chronic increases in physical …

Significance: Fatigue is one of the most common symptoms of cancer and its treatment,
manifested in the clinic through weakness and exercise intolerance. These side effects not …

Chronic inflammation is a hallmark of cancer cachexia in both patients and preclinical
models. Cachexia is prevalent in roughly 80% of cancer patients and accounts for up to 20 …