Spin hyperpolarization in modern magnetic resonance

J Eills, D Budker, S Cavagnero, EY Chekmenev… - Chemical …, 2023 - ACS Publications
Magnetic resonance techniques are successfully utilized in a broad range of scientific
disciplines and in various practical applications, with medical magnetic resonance imaging …

[HTML][HTML] NAC, NAC, Knockin'on Heaven's door: Interpreting the mechanism of action of N-acetylcysteine in tumor and immune cells

B Kalyanaraman - Redox Biology, 2022 - Elsevier
N-acetylcysteine (NAC) has been used as a direct scavenger of reactive oxygen species
(hydrogen peroxide, in particular) and an antioxidant in cancer biology and immuno …

In Vivo Metabolic Imaging of [1‐13C]Pyruvate‐d3 Hyperpolarized By Reversible Exchange With Parahydrogen**

H de Maissin, PR Groß, O Mohiuddin… - Angewandte Chemie …, 2023 - Wiley Online Library
Metabolic magnetic resonance imaging (MRI) using hyperpolarized (HP) pyruvate is
becoming a non‐invasive technique for diagnosing, staging, and monitoring response to …

Advancements in mri-based radiomics and artificial intelligence for prostate cancer: A comprehensive review and future prospects

A Chaddad, G Tan, X Liang, L Hassan, S Rathore… - Cancers, 2023 - mdpi.com
Simple Summary The integration of artificial intelligence (AI) into radiomic models has
become increasingly popular due to advances in computer-aided diagnosis tools. These …

[HTML][HTML] Metabolic imaging with deuterium labeled substrates

JCM Low, AJ Wright, F Hesse, J Cao… - Progress in Nuclear …, 2023 - Elsevier
Deuterium metabolic imaging (DMI) is an emerging clinically-applicable technique for the
non-invasive investigation of tissue metabolism. The generally short T 1 values of 2 H …

Imaging tumor lactate is feasible for identifying intermediate-risk prostate cancer patients with postsurgical biochemical recurrence

N Sushentsev, G Hamm, J Richings… - Proceedings of the …, 2023 - National Acad Sciences
While radical prostatectomy remains the mainstay of prostate cancer (PCa) treatment, 20 to
40% of patients develop postsurgical biochemical recurrence (BCR). A particularly …

Lactate as key metabolite in prostate cancer progression: what are the clinical implications?

P Chetta, R Sriram, G Zadra - Cancers, 2023 - mdpi.com
Simple Summary Advanced prostate cancer remains a clinical challenge, requiring novel
therapeutic treatments and biomarkers for patient-risk stratification. From a metabolic …

Long-lived enhanced magnetization—A practical metabolic MRI contrast material

I Katz, A Schmidt, I Ben-Shir, M Javitt, K Kouřil… - Science …, 2024 - science.org
Noninvasive tracking of biochemical processes in the body is paramount in diagnostic
medicine. Among the leading techniques is spectroscopic magnetic resonance imaging …

Hyperpolarized carbon 13 MRI: clinical applications and future directions in oncology

SS Deen, C Rooney, A Shinozaki, J McGing… - Radiology: Imaging …, 2023 - pubs.rsna.org
Hyperpolarized carbon 13 MRI (13C MRI) is a novel imaging approach that can
noninvasively probe tissue metabolism in both normal and pathologic tissues. The process …

Multi-nuclear magnetic resonance spectroscopy: State of the art and future directions

Y Wei, C Yang, H Jiang, Q Li, F Che, S Wan, S Yao… - Insights into …, 2022 - Springer
With the development of heteronuclear fluorine, sodium, phosphorus, and other probes and
imaging technologies as well as the optimization of magnetic resonance imaging (MRI) …