The tumorvirus human T-cell lymphotropic virus type 1 (HTLV-1), a member of the delta-
retrovirus family, is transmitted via cell-containing body fluids such as blood products …

Electron microscopy (EM) is an invaluable tool to study the interactions of viruses with cells,
and the ultrastructural changes induced in host cells by virus infection. Light microscopy …

Dendritic cells can capture and transfer retroviruses in vitro across synaptic cell-cell contacts
to uninfected cells, a process called trans-infection. Whether trans-infection contributes to …

The transmission of viruses from one host to another typically occurs through horizontal or
vertical pathways. The horizontal pathways include transmission amongst individuals …

The ser ine inc orporator (SERINC) proteins are multipass transmembrane proteins that
affect sphingolipid and phosphatidylserine synthesis. Human SERINC5 and SERINC3 were …

The HIV/SIV envelope glycoprotein (Env) cytoplasmic domain contains a highly conserved
Tyr-based trafficking signal that mediates both clathrin-dependent endocytosis and …

Retroviruses spread more efficiently when infected and uninfected cells form tight, physical
interfaces known as virological synapses (VSs). VS formation is initiated by adhesive …

A comprehensive understanding of host–pathogen interactions requires quantitative
assessment of molecular events across a wide range of spatiotemporal scales and …

Correlated light and electron microscopy (CLEM) has become a popular technique for
combining the protein-specific labeling of fluorescence with electron microscopy, both at …

The subcellular sites of HIV-1 assembly, determined by the localization of the structural
protein Gag, vary in a cell-type-dependent manner. In T cells and transformed cell lines used …