All serious fungal infections need appropriate antifungal therapy for successful patient outcome. Only a few classes of antifungal drugs are available, so the emergence of …
S Campoy, JL Adrio - Biochemical pharmacology, 2017 - Elsevier
The need for new antifungal agents is undeniable. Current therapeutic choices for the treatment of invasive fungal infections are limited to three classes of drugs. Most used …
MS Butler, AAB Robertson, MA Cooper - Natural product reports, 2014 - pubs.rsc.org
Covering: 2008–2013. Previous review: 2008, 25, 475 There are a significant number of natural product (NP) drugs in development. We review the 100 NP and NP-derived …
Fungi are an understudied resource possessing huge potential for developing products that can greatly improve human well-being. In the current paper, we highlight some important …
T Roemer, DJ Krysan - Cold Spring …, 2014 - perspectivesinmedicine.cshlp.org
Invasive, life-threatening fungal infections are an important cause of morbidity and mortality, particularly for patients with compromised immune function. The number of therapeutic …
Peptides are important bioactive natural products which are present in many marine species. These marine peptides have high potential nutraceutical and medicinal values …
MK Kathiravan, AB Salake, AS Chothe… - Bioorganic & medicinal …, 2012 - Elsevier
In recent years their has been an increased use of antifungal agents and has resulted in the development of resistance to drugs. Currently, use of standard antifungal therapies can be …
C Spampinato, D Leonardi - BioMed research international, 2013 - Wiley Online Library
The genus Candida includes about 200 different species, but only a few species are human opportunistic pathogens and cause infections when the host becomes debilitated or …
AH Aly, A Debbab, P Proksch - Applied microbiology and biotechnology, 2011 - Springer
Fungal endophytes residing in the internal tissues of living plants occur in almost every plant on earth from the arctic to the tropics. The endophyte–host relationship is described as a …