Pharmacological modulation of Nrf2/HO-1 signaling pathway as a therapeutic target of Parkinson's disease

Y Wang, L Gao, J Chen, Q Li, L Huo, Y Wang… - Frontiers in …, 2021 - frontiersin.org
Parkinson's disease (PD) is a complex neurodegenerative disorder featuring both motor and
nonmotor symptoms associated with a progressive loss of dopaminergic neurons in the …

Natural products attenuate PI3K/Akt/mTOR signaling pathway: A promising strategy in regulating neurodegeneration

S Fakhri, A Iranpanah, MM Gravandi, SZ Moradi… - Phytomedicine, 2021 - Elsevier
Background As common, progressive, and chronic causes of disability and death,
neurodegenerative diseases (NDDs) significantly threaten human health, while no effective …

Exploring the Paradox of COVID‐19 in Neurological Complications with Emphasis on Parkinson's and Alzheimer's Disease

SN Rai, N Tiwari, P Singh, AK Singh… - Oxidative medicine …, 2022 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is a human coronavirus
(HCoV) that has created a pandemic situation worldwide as COVID‐19. This virus can …

Mucuna pruriens in Parkinson's and in some other diseases: recent advancement and future prospective

SN Rai, VK Chaturvedi, P Singh, BK Singh, MP Singh - 3 Biotech, 2020 - Springer
Mucuna pruriens (Mp) is an annual and perennial legume which belongs to the family
Fabaceae having different types of therapeutic activity. Anti-oxidative, anti-inflammatory, anti …

Flavonoids as promising neuroprotectants and their therapeutic potential against Alzheimer's disease

T Minocha, H Birla, AA Obaid, V Rai… - Oxidative Medicine …, 2022 - Wiley Online Library
Alzheimer's disease (AD) is one of the serious and progressive neurodegenerative
disorders in the elderly worldwide. Various genetic, environmental, and lifestyle factors are …

Ferritinophagy‐mediated ferroptosis involved in paraquat‐induced neurotoxicity of dopaminergic neurons: implication for neurotoxicity in PD

Y Zuo, J Xie, X Li, Y Li, A Thirupathi… - Oxidative medicine …, 2021 - Wiley Online Library
Parkinson's disease (PD) is a progressive nervous system disorder. Until now, the molecular
mechanism of its occurrence is not fully understood. Paraquat (PQ) was identified as a …

[HTML][HTML] Protein tyrosine phosphatase 1B (PTP1B) as a potential therapeutic target for neurological disorders

J Olloquequi, A Cano, E Sanchez-López… - Biomedicine & …, 2022 - Elsevier
Protein tyrosine phosphatase 1B (PTP1B) is a typical member of the PTP family, considered
a direct negative regulator of several receptor and receptor-associated tyrosine kinases …

Biomolecules of mushroom: A recipe of human wellness

MP Singh, SN Rai, SK Dubey, AT Pandey… - Critical Reviews in …, 2022 - Taylor & Francis
The Indian system of medicine–Ayurveda says “When diet is wrong, medicine is of no use.
When diet is correct, medicine is of no use”. In this context, mushroom constitutes one of the …

Neuroprotective properties of Betulin, Betulinic acid, and Ursolic acid as triterpenoids derivatives: A comprehensive review of mechanistic studies

M Farzan, M Farzan, M Shahrani, SP Navabi… - Nutritional …, 2024 - Taylor & Francis
Cognitive deficits are the main outcome of neurological disorders whose occurrence has
risen over the past three decades. Although there are some pharmacologic approaches …

Role of specialized pro-resolving mediators in reducing neuroinflammation in neurodegenerative disorders

J Ponce, A Ulu, C Hanson, E Cameron-Smith… - Frontiers in Aging …, 2022 - frontiersin.org
Alzheimer's disease (AD) and Parkinson's disease (PD) are neurodegenerative disorders
that affect millions of individuals worldwide. As incidence of these conditions increases with …