Carbon monoxide poisoning: pathogenesis, management, and future directions of therapy

JJ Rose, L Wang, Q Xu, CF McTiernan… - American journal of …, 2017 - atsjournals.org
Carbon monoxide (CO) poisoning affects 50,000 people a year in the United States. The
clinical presentation runs a spectrum, ranging from headache and dizziness to coma and …

Carbon monoxide, hydrogen sulfide, and nitric oxide as signaling molecules in the gastrointestinal tract

G Farrugia, JH Szurszewski - Gastroenterology, 2014 - Elsevier
Carbon monoxide (CO) and hydrogen sulfide (H 2 S) used to be thought of simply as lethal
and (for H 2 S) smelly gaseous molecules; now they are known to have important signaling …

Carbon monoxide signaling: examining its engagement with various molecular targets in the context of binding affinity, concentration, and biologic response

Z Yuan, LK De La Cruz, X Yang, B Wang, Q Ma - Pharmacological Reviews, 2022 - Elsevier
Carbon monoxide (CO) has been firmly established as an endogenous signaling molecule
with a variety of pathophysiological and pharmacological functions, including …

A modern literature review of carbon monoxide poisoning theories, therapies, and potential targets for therapy advancement.

JD Roderique, CS Josef, MJ Feldman, BD Spiess - Toxicology, 2015 - Elsevier
The first descriptions of carbon monoxide (CO) and its toxic nature appeared in the literature
over 100 years ago in separate publications by Drs. Douglas and Haldane. Both men …

Carbon monoxide toxicity

KA Nañagas, SJ Penfound… - Emergency Medicine …, 2022 - emed.theclinics.com
Carbon monoxide (CO) is an insidious poison that mimics a great number of other disease
processes. The clinical presentations associated with CO toxicity may be diverse and …

NO, CO and H2S: A trinacrium of bioactive gases in the brain

R Siracusa, VA Voltarelli, AT Salinaro… - Biochemical …, 2022 - Elsevier
Oxygen and carbon dioxide are time honored gases that have direct bearing on almost all
life forms, but over the past thirty years, and in large part due to the Nobel Prize Award in …

Nitrosative stress and human disease: Therapeutic potential of denitrosylation

S Yoon, GH Eom, G Kang - International journal of molecular sciences, 2021 - mdpi.com
Proteins dynamically contribute towards maintaining cellular homeostasis. Posttranslational
modification regulates the function of target proteins through their immediate activation …

Air pollution and cardiac arrhythmias: from epidemiological and clinical evidences to cellular electrophysiological mechanisms

S Zhang, W Lu, Z Wei, H Zhang - Frontiers in cardiovascular medicine, 2021 - frontiersin.org
Cardiovascular disease is the leading cause of death worldwide and kills over 17 million
people per year. In the recent decade, growing epidemiological evidence links air pollution …

Homocysteine, vitamins B6 and folic acid in experimental models of myocardial infarction and heart failure—how strong is that link?

Z Bajic, T Sobot, R Skrbic, MP Stojiljkovic, N Ponorac… - Biomolecules, 2022 - mdpi.com
Cardiovascular diseases are the leading cause of death and the main cause of disability. In
the last decade, homocysteine has been found to be a risk factor or a marker for …

Regulation of the cardiac Na+ channel NaV1. 5 by post-translational modifications

C Marionneau, H Abriel - Journal of molecular and cellular cardiology, 2015 - Elsevier
The cardiac voltage-gated Na+ channel, Na V 1.5, is responsible for the upstroke of the
action potential in cardiomyocytes and for efficient propagation of the electrical impulse in …