Roles of the microbiota of the female reproductive tract in gynecological and reproductive health
B Zhu, Z Tao, L Edupuganti, MG Serrano… - … and Molecular Biology …, 2022 - Am Soc Microbiol
The microbiome of the female reproductive tract defies the convention that high biodiversity
is a hallmark of an optimal ecosystem. Although not universally true, a homogeneous …
is a hallmark of an optimal ecosystem. Although not universally true, a homogeneous …
The complex link between the female genital microbiota, genital infections, and inflammation
The female genital tract microbiota is part of a complex ecosystem influenced by several
physiological, genetic, and behavioral factors. It is uniquely linked to a woman's mucosal …
physiological, genetic, and behavioral factors. It is uniquely linked to a woman's mucosal …
Microbial composition predicts genital tract inflammation and persistent bacterial vaginosis in South African adolescent females
K Lennard, S Dabee, SL Barnabas… - Infection and …, 2018 - Am Soc Microbiol
Young African females are at an increased risk of HIV acquisition, and genital inflammation
or the vaginal microbiome may contribute to this risk. We studied these factors in 168 HIV …
or the vaginal microbiome may contribute to this risk. We studied these factors in 168 HIV …
Enhanced trapping of HIV-1 by human cervicovaginal mucus is associated with Lactobacillus crispatus-dominant microbiota
Cervicovaginal mucus (CVM) can provide a barrier that precludes HIV and other sexually
transmitted virions from reaching target cells in the vaginal epithelium, thereby preventing or …
transmitted virions from reaching target cells in the vaginal epithelium, thereby preventing or …
Metabolic model-based integration of microbiome taxonomic and metabolomic profiles elucidates mechanistic links between ecological and metabolic variation
Multiple molecular assays now enable high-throughput profiling of the ecology, metabolic
capacity, and activity of the human microbiome. However, to date, analyses of such multi …
capacity, and activity of the human microbiome. However, to date, analyses of such multi …
Biogenic Amines Increase the Odds of Bacterial Vaginosis and Affect the Growth of and Lactic Acid Production by Vaginal Lactobacillus spp.
Bacterial vaginosis (BV) is the most common vaginal disorder of reproductive-aged women,
yet its etiology remains enigmatic. One clinical symptom of BV, malodor, is linked to the …
yet its etiology remains enigmatic. One clinical symptom of BV, malodor, is linked to the …
Complementing 16S rRNA gene amplicon sequencing with total bacterial load to infer absolute species concentrations in the vaginal microbiome
FA Tettamanti Boshier, S Srinivasan, A Lopez… - Msystems, 2020 - Am Soc Microbiol
Whereas 16S rRNA gene amplicon sequencing quantifies relative abundances of bacterial
taxa, variation in total bacterial load between samples restricts its ability to reflect absolute …
taxa, variation in total bacterial load between samples restricts its ability to reflect absolute …
[HTML][HTML] Vaginal epithelial dysfunction is mediated by the microbiome, metabolome, and mTOR signaling
Bacterial vaginosis (BV) is characterized by depletion of Lactobacillus and overgrowth of
anaerobic and facultative bacteria, leading to increased mucosal inflammation, epithelial …
anaerobic and facultative bacteria, leading to increased mucosal inflammation, epithelial …
Two Different Species of Mycoplasma Endosymbionts Can Influence Trichomonas vaginalis Pathophysiology
Trichomonas vaginalis can host the endosymbiont Mycoplasma hominis, an opportunistic
pathogenic bacterium capable of modulating T. vaginalis pathobiology. Recently, a new …
pathogenic bacterium capable of modulating T. vaginalis pathobiology. Recently, a new …
Defining and evaluating microbial contributions to metabolite variation in microbiome-metabolome association studies
Correlation-based analysis of paired microbiome-metabolome data sets is becoming a
widespread research approach, aiming to comprehensively identify microbial drivers of …
widespread research approach, aiming to comprehensively identify microbial drivers of …