Adverse drug reactions induced by valproic acid
RM Nanau, MG Neuman - Clinical biochemistry, 2013 - Elsevier
Valproic acid is a widely-used first-generation antiepileptic drug, prescribed predominantly
in epilepsy and psychiatric disorders. VPA has good efficacy and pharmacoeconomic …
in epilepsy and psychiatric disorders. VPA has good efficacy and pharmacoeconomic …
Toxic epidermal necrolysis
FA Pereira, AV Mudgil, DM Rosmarin - Journal of the American Academy of …, 2007 - Elsevier
Toxic epidermal necrolysis (TEN) is an unpredictable, life-threatening drug reaction
associated with a 30% mortality. Massive keratinocyte apoptosis is the hallmark of TEN …
associated with a 30% mortality. Massive keratinocyte apoptosis is the hallmark of TEN …
Comparison and predictors of rash associated with 15 antiepileptic drugs
H Arif, R Buchsbaum, D Weintraub, S Koyfman… - Neurology, 2007 - AAN Enterprises
Objective: To determine predictors and relative incidence of antiepileptic drug (AED)–related
rash in patients taking all common AEDs. Methods: We reviewed 1,890 outpatients. Eighty …
rash in patients taking all common AEDs. Methods: We reviewed 1,890 outpatients. Eighty …
Rash in multicenter trials of lamotrigine in mood disorders: clinical relevance and management
JR Calabrese, JR Sullivan, CL Bowden… - Journal of Clinical …, 2002 - psychiatrist.com
Background: The rate of lamotrigineassociated rash in patients with mood disorders has not
been well characterized. The objective of this report was to determine rash rates in clinical …
been well characterized. The objective of this report was to determine rash rates in clinical …
Predictors of lamotrigine‐associated rash
LJ Hirsch, DB Weintraub, R Buchsbaum… - …, 2006 - Wiley Online Library
Purpose: To determine the predictors of lamotrigine‐associated rash (LTG‐rash) and the
incidence of serious and benign LTG‐rash to individualize risk assessment in a given …
incidence of serious and benign LTG‐rash to individualize risk assessment in a given …
Factors influencing the incidence of lamotrigine-related skin rash
ICK Wong, GE Mawer… - Annals of …, 1999 - journals.sagepub.com
OBJECTIVE: To determine the incidences of serious and nonserious lamotrigine-related
rash, determine the risk factors for lamotrigine-related rash, and evaluate the impact on the …
rash, determine the risk factors for lamotrigine-related rash, and evaluate the impact on the …
Lamotrigine as a promising approach to borderline personality: an open case series without concurrent DSM-IV major mood disorder
OC Pinto, HS Akiskal - Journal of Affective Disorders, 1998 - Elsevier
Background: Borderline personality disorder (BPD) has long defied definitive treatment.
Such failure is reflected in repeated suicidal crises, often associated with dysphoric …
Such failure is reflected in repeated suicidal crises, often associated with dysphoric …
A prospective study of adverse drug reactions to antiepileptic drugs in children
M Anderson, O Egunsola, J Cherrill, C Millward… - BMJ open, 2015 - bmjopen.bmj.com
Objectives To prospectively determine the nature and rate of adverse drug reactions (ADRs)
in children on antiepileptic drugs (AEDs) and to prospectively evaluate the effect of AEDs on …
in children on antiepileptic drugs (AEDs) and to prospectively evaluate the effect of AEDs on …
Assessing risk to benefit ratio in antiepileptic drug therapy
E Perucca, E Beghi, O Dulac, S Shorvon, T Tomson - Epilepsy research, 2000 - Elsevier
Assessment of risk to benefit ratio in patients with epilepsy is crucial in determining the need
for treatment, the choice of drugs and the use of monitoring tools such as laboratory tests …
for treatment, the choice of drugs and the use of monitoring tools such as laboratory tests …