Y Zeng, Y Gao, L He, W Ge, X Wang, T Ma… - Nanoscale …, 2024 - pubs.rsc.org
Chemotherapy and surgery remain the primary treatment modalities for cancers; however, these techniques have drawbacks, such as cancer recurrence and toxic side effects …
L Hao, N Boehnke, SK Elledge… - Proceedings of the …, 2024 - National Acad Sciences
RNA interference (RNAi) therapeutics are an emerging class of medicines that selectively target mRNA transcripts to silence protein production and combat disease. Despite the …
Glioblastoma is characterized by diffuse infiltration into surrounding healthy brain tissues, which makes it challenging to treat. Complete surgical resection is often impossible, and …
IS Pires, JR Suggs, IS Carlo, DS Yun… - Chemistry of …, 2024 - ACS Publications
Liposomes can greatly improve the pharmacokinetics of therapeutic agents due to their ability to encapsulate drugs and accumulate in target tissues. Considerable effort has been …
EM Jacob, J Huang, M Chen - Precision Clinical Medicine, 2024 - academic.oup.com
The delivery of lipid nanoparticle (LNP)-based mRNA therapeutics has captured the attention of the vaccine research community as an innovative and versatile tool for treating a …
GI Kane, CF Lusi, ML Brassil, PU Atukorale - Immuno-Oncology and …, 2024 - Elsevier
Cancer immunotherapy offers transformative promise particularly for the treatment of lethal cancers, since a correctly trained immune system can comprehensively orchestrate tumor …
MA Davis, E Cho, MH Teplensky - Journal of Materials Chemistry B, 2023 - pubs.rsc.org
Immunomodulation is a powerful therapeutic approach that harnesses the body's own immune system and reprograms it to treat diseases, such as cancer. Innate immunity is key …
I Ahmad, KKA Altameemi, MM Hani, AM Ali… - Clinical and …, 2024 - Springer
Cold tumors lack antitumor immunity and are resistant to therapy, representing a major challenge in cancer medicine. Because of the immunosuppressive spirit of the tumor …
Nanoparticles have the potential to improve disease treatment and diagnosis due to their ability to incorporate drugs, alter pharmacokinetics, and enable tissue targeting. While …