The molecular mechanisms of virus-induced human cancers

G Ameya, DJ Birri - Microbial Pathogenesis, 2023 - Elsevier
Cancer is a serious public health problem globally. Many human cancers are induced by
viruses. Understanding of the mechanisms by which oncogenic (tumorigenic) viruses induce …

Computational formulation of a multiepitope vaccine unveils an exceptional prophylactic candidate against Merkel cell polyomavirus

RR Imon, A Samad, R Alam, AA Alsaiari… - Frontiers in …, 2023 - frontiersin.org
Merkel cell carcinoma (MCC) is a rare neuroendocrine skin malignancy caused by human
Merkel cell polyomavirus (MCV), leading to the most aggressive skin cancer in humans …

Toward the identification of natural antiviral drug candidates against merkel cell polyomavirus: computational drug design approaches

AH Asseri, MJ Alam, F Alzahrani, A Khames… - Pharmaceuticals, 2022 - mdpi.com
Merkel cell carcinoma (MCC) is a rare form of aggressive skin cancer mainly caused by
Merkel cell polyomavirus (MCPyV). Most MCC tumors express MCPyV large T (LT) antigens …

Development of a therapeutic vaccine targeting Merkel cell polyomavirus capsid protein VP1 against Merkel cell carcinoma

D Xu, S Jiang, Y He, X Jin, G Zhao, B Wang - npj Vaccines, 2021 - nature.com
Merkel cell carcinoma (MCC) is a rare but aggressive skin cancer with a high mortality rate,
while Merkel cell polyomavirus (MCV) has been pointed as the causative agent of MCC. A …

[HTML][HTML] Possible association between polyomaviruses and gastrointestinal complications: a narrative review

P Shadbash, SM Hosseini, S Shoraka… - … and Hepatology From …, 2024 - ncbi.nlm.nih.gov
Polyomaviruses are a group of small, double-stranded DNA viruses that are known to be
associated with the development of certain human diseases, but there is evidence that these …

Multidisciplinary Treatment of Merkel Cell Carcinoma of the Extremities: Outcomes and Factors Associated with Poor Survival in Nodal Disease

SE Broida, XT Chen, BD Wahlig, SL Moran… - Current …, 2023 - mdpi.com
Merkel cell carcinoma (MCC) has a tendency for lymphatic spread and locoregional
recurrence, although there is little data examining the risk factors for patients with lymph …

Evidencing the presence of merkel cell polyomavirus in papillary thyroid cancer

M Ghanghareh, J Mosayebi Amroabadi… - Scientific Reports, 2021 - nature.com
Merkel cell polyomavirus (MCPyV) infects most people asymptomatically, but recent reports
indicate that the virus may be related to carcinogenesis. This study aimed to evaluate the …

Viral Diseases of the Hair and Scalp

RM Trüeb, H Dutra Rezende - Hair in Infectious Disease: Recognition …, 2023 - Springer
A virus is a submicroscopic infectious agent hat replicates exclusively within the living cells
of an organism. When infected, a host cell is often forced to rapidly produce thousands of …

Molecular survey on Merkel cell polyomavirus in patients with colorectal cancer

MHK Niya, FS Tameshkel, M Alemrajabi… - Medical Journal of …, 2018 - mji.ui.ac.id
Background: Merkel cell polyomavirus (MCV) has been associated with Merkel cell
carcinoma (MCC) in humans, and its role in other human cancers is under investigation. The …

Beta human papillomavirus and merkel cell polyomavirus in skin neoplasms

Q Lv, Y Ye, LM Li, FJ Li, YL Wu… - International Journal of …, 2020 - mednexus.org
In 1911, Peyton Rous from the Rockefeller Institute demonstrated that a transplantable,
spontaneous, spindle cell sarcoma derived from a Plymouth Rock chicken could be virally …