The development of COVID-19 treatment
Y Yuan, B Jiao, L Qu, D Yang, R Liu - Frontiers in immunology, 2023 - frontiersin.org
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused
a pandemic named coronavirus disease 2019 (COVID-19) that has become the greatest …
a pandemic named coronavirus disease 2019 (COVID-19) that has become the greatest …
Signs of immunosenescence correlate with poor outcome of mRNA COVID-19 vaccination in older adults
MÁ Palacios-Pedrero, JM Jansen, C Blume… - Nature Aging, 2022 - nature.com
Vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
effective in preventing COVID-19 hospitalization and fatal outcome. However, several …
effective in preventing COVID-19 hospitalization and fatal outcome. However, several …
The potential of Exerkines in women's COVID-19: a new idea for a better and more accurate understanding of the mechanisms behind physical exercise
The benefits of physical exercise are well-known, but there are still many questions
regarding COVID-19. Chow et al.'s 2022 study, titled Exerkines and Disease, showed that a …
regarding COVID-19. Chow et al.'s 2022 study, titled Exerkines and Disease, showed that a …
CXCL12 ameliorates neutrophilia and disease severity in SARS-CoV-2 infection
Neutrophils, particularly low-density neutrophils (LDNs), are believed to contribute to acute
COVID-19 severity. Here, we showed that neutrophilia can be detected acutely and even …
COVID-19 severity. Here, we showed that neutrophilia can be detected acutely and even …
Robust and prototypical immune responses toward COVID-19 vaccine in First Nations peoples are impacted by comorbidities
High-risk groups, including Indigenous people, are at risk of severe COVID-19. Here we
found that Australian First Nations peoples elicit effective immune responses to COVID-19 …
found that Australian First Nations peoples elicit effective immune responses to COVID-19 …
Robust SARS-CoV-2 T cell responses with common TCRαβ motifs toward COVID-19 vaccines in patients with hematological malignancy impacting B cells
Immunocompromised hematology patients are vulnerable to severe COVID-19 and respond
poorly to vaccination. Relative deficits in immunity are, however, unclear, especially after 3 …
poorly to vaccination. Relative deficits in immunity are, however, unclear, especially after 3 …
Measurement of IFN-γ and IL-2 for the assessment of the cellular immunity against SARS-CoV-2
G Safont, R Villar-Hernández, D Smalchuk… - Scientific Reports, 2024 - nature.com
The study of specific T-cell responses against SARS-CoV-2 is important for understanding
long-term immunity and infection management. The aim of this study was to assess the dual …
long-term immunity and infection management. The aim of this study was to assess the dual …
Polyfunctional antibodies: a path towards precision vaccines for vulnerable populations
Vaccine efficacy determined within the controlled environment of a clinical trial is usually
substantially greater than real-world vaccine effectiveness. Typically, this results from …
substantially greater than real-world vaccine effectiveness. Typically, this results from …
[HTML][HTML] Mechanisms and implications of IgG4 responses to SARS-CoV-2 and other repeatedly administered vaccines
AM Marchese, L Fries, H Beyhaghi, M Vadivale, M Zhu… - Journal of Infection, 2024 - Elsevier
Vaccine-induced immunoglobulin G (IgG) profiles can vary with respect to the predominant
subclasses that characterize the response. Among IgG subclasses, IgG4 is reported to have …
subclasses that characterize the response. Among IgG subclasses, IgG4 is reported to have …
A phosphodiesterase-4 inhibitor reduces lung inflammation and fibrosis in a hamster model of SARS-CoV-2 infection
Introduction The Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2)
infection involves pulmonary inflammation that can progress to acute respiratory distress …
infection involves pulmonary inflammation that can progress to acute respiratory distress …