The arrival of cell-based therapies is a revolution in medicine. However, its safe clinical
application in a rational manner depends on reliable, clinically applicable methods for …

Molecular imaging, with major advances in the development of both innovative targeted
contrast agents/particles and radiotracers, as well as various imaging technologies, is a …

The enzyme‐mediated site‐specific bioconjugation of a radioactive metal complex to a
single‐chain antibody using the transpeptidase sortase A is reported. Cage amine …

A unique two‐step modular system for site‐specific antibody modification and conjugation is
reported. The first step of this approach uses enzymatic bioconjugation with the …

Thrombosis in the context of atherosclerosis typically results in life-threatening
consequences, including acute coronary events and ischemic stroke. As such, early …

Thrombosis contributes to one in four deaths worldwide and is the cause of a large
proportion of mortality and morbidity. A reliable and rapid diagnosis of thrombosis will allow …

Positron emission tomography is the imaging modality of choice when it comes to the high
sensitivity detection of key markers of thrombosis and inflammation, such as activated …

Fibrinolytic drugs have been successfully used to manage acute thrombotic and
thromboembolic conditions. However, their narrow administration time window, rapid …

Introduction Alzheimer's disease (AD) is characterized by the misfolding and aggregation of
two major proteins: amyloid-beta (Aβ) and tau. Antibody-based PET radioligands are …

The use of fluorine-18 as a radionuclide for positron emission tomography (PET) has
become increasingly popular over the last two decades and cancer and neurology clinical …