Diabetes and diabetic complications are considered as leading causes of both morbidity
and mortality in the world. Unfortunately, routine medical treatments used for affected …

Diabetes mellitus (DM) leads to complications, the majority of which are nephropathy,
retinopathy, and neuropathy. Redox imbalance and inflammation are important components …

Objectives. Diabetic neuropathy is the most common complication of diabetes. The idea of
alterations in energy metabolism in diabetes is emerging. The biogenic antioxidant R (+) …

Backgrounds: Diabetes can cause diabetic neuropathy (DN), a nerve injury. High blood
sugar (glucose) levels can harm nerves all over your body. The nerves in your legs and feet …

Purpose The trial aimed to investigate the effectiveness of exogenous melatonin as an
adjuvant to pregabalin for relief of pain in patients suffering from painful diabetic neuropathy …

Melatonin is a hormone secreted by the pineal gland under the control of the circadian
rhythm, and is released in the dark and suppressed during the day. In the past decades …

A 62-year-old diabetologist diagnosed himself to have diabetes type-2, with an HbA1c of
9.5. Five months after lifestyle intervention and a multi-drug approach, HbA1c was 6.3 …

Neuropathic pain is a severe condition with unsatisfactory treatments. Melatonin, an
indolamine, seems to be a promising molecule suitable for this purpose due to its well …

Peripheral neuropathy (PN) is one of the most common disorders characterized by the
dysfunction or degeneration of peripheral nerves and has many different causes. PN often …

Pre-diabetes and diabetes are growing threats to the modern world. Diabetes mellitus (DM)
is associated with comorbidities such as hypertension (83.40%), obesity (90.49%), and …