Nanomedicines for antitumour therapy have been widely studied in recent decades, but only
a few have been used in clinical applications. One of the most important reasons is the poor …

Simple Summary The tumor microenvironment encompasses the cellular and extracellular
matrix components that support and shape the three-dimensional framework in which solid …

Cancer is one of the most important mortality in the world. The major drawbacks of
chemotherapy are the poor absorption of drugs into tumor tissues and development of …

Elevated interstitial fluid pressure (IFP) within pathological tissues (eg, tumors, obstructed
kidneys, and cirrhotic livers) creates a significant hindrance to the transport of …

Low tumor enrichment remains a serious and urgent problem for drug delivery in cancer
therapy. Accurate targeting to tumor site is still a critical aim in cancer therapy. Though there …

To selectively and continuously produce anti-cancer molecules specifically in malignant
tumors, we have established an in situ delivery and production system (i DPS) with …

Background Attenuated live bacterial therapy and medical BSA materials have their own
advantages in anti-cancer research, and their combination is expected to overcome some of …

Living therapy based on bacterial cells has gained increasing attention for their applications
in tumor treatments. Bacterial cells can naturally target to tumor sites and active the innate …

Bacteria have been explored for their potential in fighting against cancer for decades. Due to
their outstanding tumor‐targeting capacity and high biocompatibility, live bacteria can serve …

One of the principal impediments to the broad success of conventional chemotherapy is
poor delivery to and transport within the tumor microenvironment (TME), caused by irregular …