New genes as drivers of phenotypic evolution

S Chen, BH Krinsky, M Long - Nature Reviews Genetics, 2013 - nature.com
During the course of evolution, genomes acquire novel genetic elements as sources of
functional and phenotypic diversity, including new genes that originated in recent evolution …

[HTML][HTML] A CRISPR–Cas9 gene drive targeting doublesex causes complete population suppression in caged Anopheles gambiae mosquitoes

K Kyrou, AM Hammond, R Galizi, N Kranjc, A Burt… - Nature …, 2018 - nature.com
In the human malaria vector Anopheles gambiae, the gene doublesex (Agdsx) encodes two
alternatively spliced transcripts, dsx-female (AgdsxF) and dsx-male (AgdsxM), that control …

The role of sex chromosomes in sexual dimorphism: discordance between molecular and phenotypic data

R Dean, JE Mank - Journal of Evolutionary Biology, 2014 - academic.oup.com
In addition to initial sex determination, genes on the sex chromosomes are theorized to play
a particularly important role in phenotypic differences between males and females. Sex …

[图书][B] The evolution of sex determination

LW Beukeboom, N Perrin - 2014 - books.google.com
Sexual reproduction is a fundamental aspect of life. It is defined by the occurrence of meiosis
and the fusion of two gametes of different sexes or mating types. Sex-determination …

A synthetic sex ratio distortion system for the control of the human malaria mosquito

R Galizi, LA Doyle, M Menichelli, F Bernardini… - Nature …, 2014 - nature.com
It has been theorized that inducing extreme reproductive sex ratios could be a method to
suppress or eliminate pest populations. Limited knowledge about the genetic makeup and …

We can't all be supermodels: the value of comparative transcriptomics to the study of non‐model insects

SJ Oppenheim, RH Baker, S Simon… - Insect molecular …, 2015 - Wiley Online Library
Insects are the most diverse group of organisms on the planet. Variation in gene expression
lies at the heart of this biodiversity and recent advances in sequencing technology have …

Rapid evolution of female-biased genes among four species of Anopheles malaria mosquitoes

F Papa, N Windbichler, RM Waterhouse… - Genome …, 2017 - genome.cshlp.org
Understanding how phenotypic differences between males and females arise from the sex-
biased expression of nearly identical genomes can reveal important insights into the biology …

High-resolution transcriptional profiling of Anopheles gambiae spermatogenesis reveals mechanisms of sex chromosome regulation

C Taxiarchi, N Kranjc, A Kriezis, K Kyrou… - Scientific reports, 2019 - nature.com
Although of high priority for the development of genetic tools to control malaria-transmitting
mosquitoes, only a few germline-specific regulatory regions have been characterised to date …

Exploiting a Y chromosome-linked Cas9 for sex selection and gene drive

S Gamez, D Chaverra-Rodriguez, A Buchman… - Nature …, 2021 - nature.com
CRISPR-based genetic engineering tools aimed to bias sex ratios, or drive effector genes
into animal populations, often integrate the transgenes into autosomal chromosomes …

Masculinization of the X chromosome in the pea aphid

J Jaquiéry, C Rispe, D Roze, F Legeai… - PLoS …, 2013 - journals.plos.org
Evolutionary theory predicts that sexually antagonistic mutations accumulate differentially on
the X chromosome and autosomes in species with an XY sex-determination system, with …