Metabolic-associated fatty liver disease (MAFLD) refers to the build-up of fat in the liver
associated with metabolic dysfunction and has been estimated to affect a quarter of the …

Purpose Nonalcoholic fatty liver (NAFL) is a major contributor to pediatric liver disease. This
review evaluated the current literature on prevalence, screening, diagnosis, and …

Abstract Background/Objectives Sex-specific differences in obesity-related metabolic
characteristics of non-alcoholic fatty liver disease (NAFLD) have rarely been explored …

Fetal overnutrition predisposes offspring to increased metabolic risk. The current study used
metabolomics to assess sustained differences in serum metabolites across childhood and …

Objectives: To evaluate the effect of extreme weight loss programs on circulating metabolites
and their relationship with cardiometabolic health in children with metabolic syndrome …

ALDH1L1 (10-formyltetrahydrofolate dehydrogenase), an enzyme of folate metabolism, is
highly expressed in the liver. It regulates the overall flux of folate-bound one-carbon groups …

Objectives Metabolic dysfunction‐associated steatotic liver disease (MASLD) is the most
common pediatric liver disease and can progress to liver fibrosis. Latino adolescents have …

Here, we seek to identify metabolite predictors of dysglycemia in youth. In the discovery
analysis among 391 youth in the Exploring Perinatal Outcomes among CHildren (EPOCH) …

The objective of this study was to assess intermediary metabolic alterations that link sugar-
sweetened beverage (SSB) intake to cardiometabolic (CM) risk factors in youth. A total of …