Bone physiology relies on the delicate balance between resorption and formation of its
tissue. Bone resorption depends on a process called osteoclastogenesis in which bone …

Formation of autoantibodies to carbamylated proteins (anti-CarP) is considered detrimental
in the prognosis of erosive rheumatoid arthritis (RA). The source of carbamylated antigens …

Background Patients with rheumatoid arthritis (RA) have increased levels of interleukin-18
(IL-18) and decreased levels of IL-18 binding protein (IL-18BP) in the serum and synovial …

Globally, osteoporosis is the most common systemic skeletal disease. There are many
factors that influence osteoporosis' development and progression. During the pathogenesis …

Osteoclasts are multinucleated bone resorbing cells that can be differentiated from human
monocytes in vitro. There are few studies comparing osteoclastogenesis of different …

Osteoporosis is characterized by a progressive increase in bone fragility, leading to low
bone mass and structural deterioration of bone tissue. MicroRNA‐155 (miR‐155) is highly …

Osteoclasts, the bone resorbing cells of hematopoietic origin formed by macrophage fusion,
are essential in bone health and disease. However, in vitro research on osteoclasts remains …

Multinucleated osteoclasts, essential for skeletal remodeling in health and disease, are
formed by the fusion of osteoclast precursors, where each fusion event raises their bone …

It is accepted that biomimetic supply of signaling molecules during bone regeneration can
provide an appropriate environment for accelerated new bone formation. In this study, we …

Introduction Immune checkpoint inhibitors are used in the treatment of various cancers and
have been extensively researched with regard to inflammatory and autoimmune diseases …