Immunogenicity of decellularized extracellular matrix scaffolds: a bottleneck in tissue engineering and regenerative medicine

M Kasravi, A Ahmadi, A Babajani… - Biomaterials …, 2023 - spj.science.org
Tissue-engineered decellularized extracellular matrix (ECM) scaffolds hold great potential to
address the donor shortage as well as immunologic rejection attributed to cells in …

[HTML][HTML] Vascular tissue engineering: progress, challenges, and clinical promise

HHG Song, RT Rumma, CK Ozaki, ER Edelman… - Cell stem cell, 2018 - cell.com
Although the clinical demand for bioengineered blood vessels continues to rise, current
options for vascular conduits remain limited. The synergistic combination of emerging …

Extracellular matrix-based biomaterials and their influence upon cell behavior

MC Cramer, SF Badylak - Annals of biomedical engineering, 2020 - Springer
Biologic scaffold materials composed of allogeneic or xenogeneic extracellular matrix (ECM)
are commonly used for the repair and remodeling of injured tissue. The clinical outcomes …

[HTML][HTML] Commercialization and regulation of regenerative medicine products: Promises, advances and challenges

N Beheshtizadeh, M Gharibshahian… - Biomedicine & …, 2022 - Elsevier
The ultimate goal of regenerative medicine is to repair, regenerate, or reconstruct functional
loss in failed tissues and/or organs. Although regenerative medicine is a relatively new field …

The host response to naturally-derived extracellular matrix biomaterials

AH Morris, DK Stamer, TR Kyriakides - Seminars in immunology, 2017 - Elsevier
Biomaterials based on natural materials including decellularized tissues and tissue-derived
hydrogels are becoming more widely used for clinical applications. Because of their native …

Inflammation-mediated matrix remodeling of extracellular matrix-mimicking biomaterials in tissue engineering and regenerative medicine

M Xu, T Su, X Jin, Y Li, Y Yao, K Liu, K Chen, F Lu… - Acta Biomaterialia, 2022 - Elsevier
Extracellular matrix (ECM)-mimicking biomaterials are considered effective tissue-
engineered scaffolds for regenerative medicine because of their biocompatibility …

[HTML][HTML] Extracellular matrix scaffold-immune microenvironment modulates tissue regeneration

Y Yu, W Zhang, X Liu, H Wang, J Shen, H Xiao… - Composites Part B …, 2022 - Elsevier
A promising paradigm to regenerative medicine involves the application of biomaterials,
which makes a spurt of progress in the past 20 years. Of various biomaterials, decellularized …

Engineering blood vessels and vascularized tissues: technology trends and potential clinical applications

P Chandra, A Atala - Clinical Science, 2019 - portlandpress.com
Vascular tissue engineering has the potential to make a significant impact on the treatment
of a wide variety of medical conditions, including providing in vitro generated vascularized …

Renal regeneration: the role of extracellular matrix and current ECM‐based tissue engineered strategies

R Sobreiro‐Almeida, R Quinteira… - Advanced healthcare …, 2021 - Wiley Online Library
Natural extracellular matrices (ECM) are currently being studied as an alternative source for
organ transplantation or as new solutions to treat kidney injuries, which can evolve to end …

Regulation of decellularized tissue remodeling via scaffold-mediated lentiviral delivery in anatomically-shaped osteochondral constructs

CR Rowland, KA Glass, AR Ettyreddy, CC Gloss… - Biomaterials, 2018 - Elsevier
Cartilage-derived matrix (CDM) has emerged as a promising scaffold material for tissue
engineering of cartilage and bone due to its native chondroinductive capacity and its ability …