[HTML][HTML] Thiolated polymeric hydrogels for biomedical application: Cross-linking mechanisms

S Summonte, GF Racaniello, A Lopedota… - Journal of Controlled …, 2021 - Elsevier
This review focuses on the synthesis of hydrogel networks using thiomers such as thiolated
hyaluronic acid, chitosan, cyclodextrin, poly (ethylene glycol) and dextran that are cross …

Thiolated chitosans: A multi-talented class of polymers for various applications

C Federer, M Kurpiers… - Biomacromolecules, 2020 - ACS Publications
Various properties of chitosan can be customized by thiolation for very specific needs in a
wide range of application areas. Since the discovery of thiolated chitosans, many studies …

Naturally occurring polyelectrolytes and their use for the development of complex-based mucoadhesive drug delivery systems: an overview

R Cazorla-Luna, A Martín-Illana, F Notario-Pérez… - Polymers, 2021 - mdpi.com
Biopolymers have several advantages for the development of drug delivery systems, since
they are biocompatible, biodegradable and easy to obtain from renewable resources …

Thiolated polymers: Bioinspired polymers utilizing one of the most important bridging structures in nature

C Leichner, M Jelkmann… - Advanced Drug Delivery …, 2019 - Elsevier
Thiolated polymers designated “thiomers” are obtained by covalent attachment of thiol
functionalities on the polymeric backbone of polymers. In 1998 these polymers were first …

Thiolation of biopolymers for developing drug delivery systems with enhanced mechanical and mucoadhesive properties: A review

V Puri, A Sharma, P Kumar, I Singh - Polymers, 2020 - mdpi.com
Biopolymers are extensively used for developing drug delivery systems as they are easily
available, economical, readily modified, nontoxic, biodegradable and biocompatible …

[HTML][HTML] Amino acid-grafted and N-acylated chitosan thiomers: Construction of 3D bio-scaffolds for potential cartilage repair applications

FGLM Borsagli, IC Carvalho, HS Mansur - International journal of biological …, 2018 - Elsevier
In this work novel three-dimensional (3D) scaffolds were developed with chitosan thiomer
derivatives for potential soft tissue repair applications. Amino acid-grafted chitosan (cysteine …

Thiol-and disulfide-based stimulus-responsive soft materials and self-assembling systems

DM Beaupre, RG Weiss - Molecules, 2021 - mdpi.com
Properties and applications of synthetic thiol-and disulfide-based materials, principally
polymers, are reviewed. Emphasis is placed on soft and self-assembling materials in which …

Therapeutic medications against diabetes: what we have and what we expect

C Hu, W Jia - Advanced Drug Delivery Reviews, 2019 - Elsevier
Diabetes has become one of the largest global health and economic burdens, with its
increased prevalence and high complication ratio. Stable and satisfactory blood glucose …

Thiolated pectin-chitosan composites: Potential mucoadhesive drug delivery system with selective cytotoxicity towards colorectal cancer

TE Leonard, AF Liko, M Gustiananda, ABN Putra… - International Journal of …, 2023 - Elsevier
Mucoadhesive drug delivery systems (DDS) may promote safer chemotherapy for colorectal
cancer (CRC) by maximizing local drug distribution and residence time. Carbohydrate …

Engineered horseradish peroxidase-catalyzed hydrogels with high tissue adhesiveness for biomedical applications

TTH Thi, Y Lee, P Le Thi, KD Park - Journal of Industrial and Engineering …, 2019 - Elsevier
Adhesive hydrogels offer considerable potential in biomedical applications because of the
excellent integration between materials and tissues. Horseradish peroxidase (HRP) …