[HTML][HTML] Actinobacteria in natural products research: Progress and prospects

PA Jose, A Maharshi, B Jha - Microbiological research, 2021 - Elsevier
Actinobacteria are well-recognised biosynthetic factories that produce an extensive
spectrum of secondary metabolites. Recent genomic insights seem to impact the exploitation …

Structural diversity, biosynthesis, and biological functions of lipopeptides from Streptomyces

S Zhang, Y Chen, J Zhu, Q Lu, MJ Cryle… - Natural Product …, 2023 - pubs.rsc.org
Covering: up to 2022 Streptomyces are ubiquitous in terrestrial and marine environments,
where they display a fascinating metabolic diversity. As a result, these bacteria are a prolific …

Bioactive metabolites from terrestrial and marine actinomycetes

C Ngamcharungchit, N Chaimusik, W Panbangred… - Molecules, 2023 - mdpi.com
Actinomycetes inhabit both terrestrial and marine ecosystems and are highly proficient in
producing a wide range of natural products with diverse biological functions, including …

Recent progress of antibacterial natural products: Future antibiotics candidates

J Dai, R Han, Y Xu, N Li, J Wang, W Dan - Bioorganic chemistry, 2020 - Elsevier
The discovery of novel antibacterial molecules plays a key role in solving the current
antibiotic crisis issue. Natural products have long been an important source of drug …

Structure elucidation of bacterial nonribosomal lipopeptides

S Götze, P Stallforth - Organic & Biomolecular Chemistry, 2020 - pubs.rsc.org
Nonribosomal lipopeptides (NRLPs) are complex natural products of bacterial origin that not
only fulfill important ecological functions but also serve as lead structures for the …

Metabolic blockade-based genome mining reveals lipochain-linked dihydro-β-alanine synthetases involved in autucedine biosynthesis

H Zhang, C Zhang, Q Li, J Ma, J Ju - Organic Letters, 2022 - ACS Publications
Continuously mining the Streptomyces olivaceus SCSIO T05 genome leads to the
identification of new lipopeptides (autucedines A–C), constituting members of the 10th …

Antibacterial natural products from microbial and fungal sources: A decade of advances

S Mohan, MS Ajay Krishna, M Chandramouli, RS Keri… - Molecular Diversity, 2023 - Springer
Throughout the ages the world has witnessed the outbreak of many infectious diseases.
Emerging microbial diseases pose a serious threat to public health. Increasing resistance of …

Rapid Discovery of Substances with Anticancer Potential from Marine Fungi Based on a One Strain–Many Compounds Strategy and UPLC-QTOF-MS

YT Wu, XN Zhao, PX Zhang, CF Wang, J Li, XY Wei… - Marine Drugs, 2023 - mdpi.com
The secondary metabolites of marine fungi with rich chemical diversity and biological activity
are an important and exciting target for natural product research. This study aimed to …

Genome-Led Discovery of the Antibacterial Cyclic Lipopeptide Kutzneridine A and Its Silent Biosynthetic Gene Cluster from Kutzneria Species

FJ Ortiz-López, D Oves-Costales… - Journal of Natural …, 2024 - ACS Publications
Genome analysis of Kutzneria sp. CA-103260 revealed a putative lipopeptide-encoding
biosynthetic gene cluster (BGC) that was cloned into a bacterial artificial chromosome (BAC) …

Discovery and Biosynthesis of Bolagladins: Unusual Lipodepsipeptides from Burkholderia gladioli Clinical Isolates**

Y Dashti, IT Nakou, AJ Mullins, G Webster… - Angewandte …, 2020 - Wiley Online Library
Two Burkholderia gladioli strains isolated from the lungs of cystic fibrosis patients were
found to produce unusual lipodepsipeptides containing a unique citrate‐derived fatty acid …