Immune modulation by mesenchymal stem cells

W Jiang, J Xu - Cell proliferation, 2020 - Wiley Online Library
Mesenchymal stem cells (MSCs) can be derived from various adult tissues with multipotent
and self‐renewal abilities. The characteristics of presenting no major ethical concerns …

Immunoregulation by mesenchymal stem cells: biological aspects and clinical applications

ME Castro-Manrreza… - Journal of immunology …, 2015 - Wiley Online Library
Mesenchymal stem cells (MSCs) are multipotent cells capable of differentiation into
mesenchymal lineages and that can be isolated from various tissues and easily cultivated in …

Immunosuppressive properties of mesenchymal stem cells: advances and applications

MP De Miguel, S Fuentes-Julian… - Current molecular …, 2012 - ingentaconnect.com
Mesenchymal stem cells (MSCs) have been isolated from a variety of tissues, such as bone
marrow, skeletal muscle, dental pulp, bone, umbilical cord and adipose tissue. MSCs are …

Mechanisms of mesenchymal stromal cell immunomodulation

K English - Immunology and cell biology, 2013 - Wiley Online Library
Multipotent mesenchymal stromal cells (MSCs) have generated considerable interest in the
fields of regenerative medicine, cell therapy and immune modulation. Over the past 5 years …

Immunoregulatory effects of mesenchymal stem cell-derived extracellular vesicles on T lymphocytes

A Del Fattore, R Luciano, L Pascucci… - Cell …, 2015 - journals.sagepub.com
The immunomodulatory activity of mesenchymal stem cells (MSCs) is largely mediated by
paracrine factors. We have recently shown that the immunosuppressive effects of MSCs on …

Mesenchymal stem cells from umbilical cord matrix, adipose tissue and bone marrow exhibit different capability to suppress peripheral blood B, natural killer and T …

A Ribeiro, P Laranjeira, S Mendes, I Velada… - Stem cell research & …, 2013 - Springer
Introduction The ability to self-renew, be easily expanded in vitro and differentiate into
different mesenchymal tissues, render mesenchymal stem cells (MSCs) an attractive …

Human adipose tissue-derived mesenchymal stem cells abrogate plasmablast formation and induce regulatory B cells independently of T helper cells

M Franquesa, FK Mensah, R Huizinga, T Strini… - Stem …, 2015 - academic.oup.com
Mesenchymal or stromal stem cells (MSC) interact with cells of the immune system in
multiple ways. Modulation of the immune system by MSC is believed to be a therapeutic …

Mesenchymal stromal cell-derived exosomes affect mRNA expression and function of B-lymphocytes

D Khare, R Or, I Resnick, C Barkatz… - Frontiers in …, 2018 - frontiersin.org
Background: Bone marrow mesenchymal stem cells (bmMSC) may play a role in the
regulation of maturation, proliferation, and functional activation of lymphocytes, though the …

Mesenchymal stromal cells infusions improve refractory chronic graft versus host disease through an increase of CD5+ regulatory B cells producing interleukin 10

Y Peng, X Chen, Q Liu, X Zhang, K Huang, L Liu, H Li… - Leukemia, 2015 - nature.com
Refractory chronic graft-versus-host disease (cGVHD) is a significant complication resulting
from allogeneic hematopoietic stem cell transplantation (HSCT). Mesenchymal stromal cells …

[HTML][HTML] Mesenchymal stem cells suppress B-cell terminal differentiation

S Asari, S Itakura, K Ferreri, CP Liu, Y Kuroda… - Experimental …, 2009 - Elsevier
OBJECTIVE: Mesenchymal stem cells (MSCs) have been shown to possess
immunomodulatory properties on a diverse array of immune cell lineages. However, their …