Bioprinting is an emerging technology with various applications in making functional tissue
constructs to replace injured or diseased tissues. It is a relatively new approach that …

Tumour necrosis factor (TNF) is a pro-inflammatory cytokine that has important roles in
mammalian immunity and cellular homeostasis. Deregulation of TNF receptor (TNFR) …

Background & Aims Anti–tumor necrosis factor (anti-TNF) therapies are the most widely
used biologic drugs for treating immune-mediated diseases, but repeated administration can …

Atherosclerosis is a common pathology present in many cardiovascular diseases. Although
the current therapies (including statins and inhibitors of the serine protease PCSK9) can …

Cyclodextrin (CD) is one of the most versatile substances produced by nature and can form
supramolecular hydrogels with polymers or small molecules based on non-covalent …

In the last century, small-molecule natural products were the main inspiration for most drug
discovery programs based either on high-throughput screening (HTS) or rational design …

Inflammatory bowel disease (IBD) is a chronic gastrointestinal tract disorder characterized
by uncontrolled inflammatory responses to the disrupted intestinal epithelial barrier and gut …

Biological molecules are increasingly becoming a part of the therapeutics portfolio that has
been either recently approved for marketing or those that are in the pipeline of several …

Despite the beneficial therapeutic effects of intravenous immunoglobulin (IVIg) in
inflammatory diseases, consistent therapeutic efficacy and potency remain major limitations …

The ischemic stroke is a major global health concern, with high mortality and disability rates.
Unfortunately, there is a dearth of effective clinical interventions for managing poststroke …