Telomeres are nucleoprotein structures that cap the end of each chromosome arm and
function to maintain genome stability. The length of telomeres is known to shorten with each …

Telomeres are nucleoprotein caps flanking DNA. They are shortened by cell division and
oxidative stress and are lengthened by the enzyme telomerase and DNA exchange during …

Telomeres in most human cells shorten with each round of DNA replication, because they
lack the enzyme telomerase. This is not, however, the only determinant of the rate of loss of …

OBJECTIVE: To provide a systematic review of the relationship between age and leukocyte
telomere length (LTL) in adults. METHODS: Relevant studies were identified by a systematic …

This review describes the structure of telomeres, the protective DNA-protein complexes at
eukaryotic chromosomal ends, and several molecular mechanisms involved in telomere …

The identification and validation of biomarkers for diagnosing Alzheimer's disease (AD) and
other forms of dementia are increasingly important. To date, ELISA measurement of β …

Background It is widely believed that females have longer telomeres than males, although
results from studies have been contradictory. Methods We carried out a systematic review …

The telomere length of replicating somatic cells is inversely correlated with age and has
been reported to be associated cross-sectionally with cardiovascular disease (CVD) …

Understanding the malleable determinants of cellular aging is critical to understanding
human longevity. Telomeres may provide a pathway for exploring this question. Telomeres …

Telomeres, the DNA–protein structures located at the ends of chromosomes, have been
proposed to act as a biomarker of aging. In this review, the human evidence that telomere …