Allenes are the simplest class of cumulenes, with two contiguous C C bonds, and show
unique physical and chemical properties. These features make allenes particularly attractive …

Allenes are a class of unique compounds with two π-orbitals perpendicular to each other.
The first synthesis can be traced back to 1887. 1 They also exist in many natural products …

The Pauson±Khand (P±K) reaction, formally a [21211] cycloaddition involving an alkene, an
alkyne and carbon monoxide moieties to form a cyclopentenone, was first discovered in the …

Covering: 2000–2018 In this review, we highlight recent examples of natural product total
syntheses employing transition metal-mediated/catalyzed carbonylative cyclization …

Allene–Verbindungen mit zwei benachbarten C C‐Bindungen–bilden die einfachste
Klasse unter den Cumulenen. Sie verfügen über außergewöhnliche physikalische und …

The [2+ 2+ 1] cyclization of an alkyne, an alkene and carbon monoxide, ie, the Pauson–
Khand reaction, is one of the most powerful tools for constructing a five-membered ring. In …

Treatment of alkynyl allenes with [Rh (CO) 2Cl] 2 results in a formal [2+ 2+ 1] cycloaddition
reaction. This reaction occurs with complete regioselectivity for a variety of substrates …

(AOR) or leukotriene B4 12-hydroxydehydrogenase, reductively activates AFs. 54 AFs
interact with redox-modulating enzymes, such as glutathione reductase (GR), thioredoxin …

A Pauson− Khand type conversion of enynes to bicyclic cyclopentenones employing the
commercially available precatalyst titanocene dicarbonyl is described. This methodology …

The use of transition metal-centred reagents in organic synthesis is now commonplace.
These reagents are used to perform highly regio-and stereo-selective bond forming …